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Items 1 to 30 of 401 total

  1. Nocodazole, Microtubule Inhibitor / CRISPR Editing Enhancer

    Catalog No. M60331
    A potent microtubule inhibitor to inhibit mitosis and CRISPR editing enhancer.
  2. (+)-JQ1, BET Inhibitor

    $109.00   $139.00
    Catalog No. M60139
    A potent and selective inhibitor of the bromodomain and extra terminal (BET) family proteins BRD2, BRD3, and BRD4
  3. (R)-2-HG, a-KG-dependent dioxygenases inhibitor

    Catalog No. M60104
    An a-KG-dependent dioxygenases inhibitor
  4. (S)-crizotinib, MTH1 Inhibitor

    Catalog No. M60208
    A novel potent, selective and cell permeable MTH1 inhibitor.
  5. (Z)-4-Hydroxytamoxifen, CRISPR Editing Enhancer

    Catalog No. M60324
    Previously characterized as an Estrogen Receptor antagonist and now found to improve genome-editing specificity in CRISPR-mediated gene editing
  6. 1,4-DPCA, Prolyl 4-hydroxylase (P4H) Inhibitor

    Catalog No. M60288
    A selective and cell permeable prolyl 4-hydroxylase (P4H) inhibitor.
  7. 1-methyl-D-tryptophan (D-1MT), IDO Inhibitor

    Catalog No. M60291
    A potent and selective indoleamine 2,3-dioxygenase (IDO) inhibitor.
  8. 4SC-202, HDAC/LSD1 Dual Inhibitor

    Catalog No. M60230
    A potent, selective and orally bioavailable HDAC/LSD1 dual Inhibitor.
  9. 5-Azacytidine, DNA Methyltransferase Inhibitor

    Catalog No. M60131
    A classic DNA methyltransferase inhibitor, incorporates into DNA forming covalent adducts with cellular DNMT, depleting enzyme activity.
  10. A-366, G9a/GLP HMTase Inhibitor

    Catalog No. M60210
    A novel highly potent, selective and cell permeable G9a/GLP histone lysine methyltransferase inhibitor.
  11. A01, Smurf1 E3 Ubiquitin Ligase Inhibitor

    Catalog No. M60249
    A potent and selective Smurf1 E3 ubiquitin ligase inhibitor.
  12. A769662, AMPK Activator

    Catalog No. M60020
    A potent allosteric AMPK activator.
  13. A83-01, TGF-β Inhibitor

    Catalog No. M60021
    A potent and selective TGF-β pathway inhibitor (targeting ALK4, ALK5 and ALK7).
  14. AA92593, Antagonist of Melanopsin-mediated Photo-transduction

    Catalog No. M60143
    A potent and selective small molecule antagonist of melanopsin-mediated photo-transduction.
  15. Abiraterone, CYP17 inhibitor Abiraterone (CB-7598)

    Catalog No. M60031
    A first-in-class CYP17 inhibitor approved to treat castration-resistant prostate cancer.
  16. ABT-199, BCL-2 inhibitor

    Catalog No. M60075
    A potent BCL-2–selective (BCL-X L) inhibitor with clinical efficacy.
  17. ACY-1215 (Rocilinostat), HDAC6 inhibitor

    Catalog No. M60076
    A highly potent, selective, and orally bioavailable inhibitor of histone deacetylase 6 (HDAC6).
  18. ADC Toxin Monomethyl auristatin E (MMAE)

    Catalog No. T60001
    Antimitotic agent used as toxin linked to antibody.
  19. ADC Toxin Monomethyl auristatin F (MMAF)

    Catalog No. T60002
    Antimitotic agent used as toxin linked to antibody
  20. AdipoRon, Adiponectin Receptor/AdipoR agonist

    Catalog No. M60152
    A novel, highly potent, selective and orally active small molecule agonist of adiponectin receptor (AdipoR).
  21. AG-120 (Ivosidenib), IDH1 Inhibitor

    Catalog No. M60318
    A potent, selective and reversible inhibitor of IDH1 in clinical trials.
  22. AG-221 (Enasidenib), IHD2 Inhibitor

    Catalog No. M60296
    A potent and selective inhibitor of IDH2 R140Q mutant.
  23. AGI-5198 (IDH-C35), Mutant IDH1 Inhibitor

    Catalog No. M60068
    The first highly potent and selective mutant IDH1 inhibitor that was shown to have anti-tumor efficacy in vivo.
  24. AGI-6780, Mutant IDH2 Inhibitor

    Catalog No. M60105
    The first highly potent and selective small molecule mutant IDH2 inhibitor.
  25. AK-7, SIRT2 Inhibitor

    Catalog No. M60107
    A cell- and brain-permeable, selective sirtuin SIRT2 inhibitor, displays no effect on SIRT1 or SIRT3.
  26. AMI-1, Histone Methyltransferase Inhibitor

    Catalog No. M60272
    A potent and specific small molecule inhibitor of histone methyltransferase targeting yeast Hmt1p and human PRMT1.
  27. APY29, IRE1a Modulator

    Catalog No. M60168
    A highly potent and selective small molecule modulator of IRE1α.
  28. AR7, RARα antagonist

    Catalog No. M60116
    A highly potent and selective enhancer of the chaperone-mediated autophagy (CMA) through antagonizing RARα.
  29. AS2034178, GPR40 Agonist

    Catalog No. M60221
    A potent, selective and orally bioavailable GPR40 (FFA1) agonist.
  30. AS8351, KDM5B Inhibitor

    Catalog No. M60330
    A potent iron chelator that has been found to inhibit of histone demethylase KDM5B (JARID1B).

Items 1 to 30 of 401 total