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Anti-cancer

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  1. Abiraterone, CYP17 inhibitor Abiraterone (CB-7598)

    $69.00
    Catalog No. M60031
    A first-in-class CYP17 inhibitor approved to treat castration-resistant prostate cancer.
  2. ABT-199, BCL-2 inhibitor

    $99.00
    Catalog No. M60075
    A potent BCL-2–selective (BCL-X L) inhibitor with clinical efficacy.
  3. AG-120 (Ivosidenib), IDH1 Inhibitor

    $129.00
    Catalog No. M60318
    A potent, selective and reversible inhibitor of IDH1 in clinical trials.
  4. AG-221 (Enasidenib), IHD2 Inhibitor

    $129.00
    Catalog No. M60296
    A potent and selective inhibitor of IDH2 R140Q mutant.
  5. APY29, IRE1a Modulator

    $109.00
    Catalog No. M60168
    A highly potent and selective small molecule modulator of IRE1α.
  6. AZD6244 (Selumetinib), MEK Inhibitor

    $109.00
    Catalog No. M60067
    A potent and highly selective non-ATP competitive MEK inhibitor in clinical trials.
  7. Azidothymidine (AZT), Reverse Transcriptase Inhibitor

    $29.00
    Catalog No. M60238
    A selective, orally bioavailable and brain penetrant reverse transcriptase inhibitor.
  8. b-AP15 (NSC687852), Deubiquitinases Inhibitor

    $89.00
    Catalog No. M60251
    A potent and selective deubiquitinases inhibitor for 19S proteasomes activity of Ub-AMC cleavage.
  9. BAM7, BAX Activator

    $109.00
    Catalog No. M60069
    The first potent and selective small molecule activator of BAX, which is a pro-apoptotic BCL-2 family member.
  10. BAY 87-2243, Hypoxia-inducible Factor-1 (HIF-1) Inhibitor

    $119.00
    Catalog No. M60217
    A highly potent and selective hypoxia-inducible factor-1 (HIF-1) inhibitor.
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