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  1. FLI-06, Notch Pathway Modulator

    Catalog No. M60149
    FLI-06 is a novel potent and selective small molecule intercepting Notch signaling and the early secretory pathway (EC50 ~2.3 µM), identified by using automated microscopy to monitor the trafficking and processing of a ligand-independent Notch-GFP fusion reporter.
  2. Forskolin, Adenylyl Cyclase Activator

    Catalog No. M60024
    A potent adenylate cyclase activator to increase the intracellular levels of cAMP.
  3. Furamidine, PRMT1 Inhibitor

    Catalog No. M60256
    A potent, selective and cell permeable Protein arginine methyltransferase-1 (PRMT1) inhibitor.
  4. GDC-0068, Akt Inhibitor

    Catalog No. M60066
    A novel potent and selective ATP competitive Akt inhibitor in clinical trials.
  5. GDC-0349, mTOR Inhibitor

    Catalog No. M60110
    A potent and selective ATP-competitive inhibitor of mTOR in clinical trials.
  6. GDC-0449 (Vismodegib), Hedgehog Antagonist

    Catalog No. M60034
    A potent and specific hedgehog pathway inhibitor approved by FDA
  7. GDC-0941, PI3K Inhibitor

    Catalog No. M60111
    A highly potent, selective and orally bioavailable class-I PI3K kinase inhibitor.
  8. GN44028, HIF-1α Inhibitor

    Catalog No. M60325
    A potent and selective HIF-1α inhibitor.
  9. GNF-7, Ras Signaling Inhibitor

    Catalog No. M60281
    A potent, selective and bioavailable Ras signaling inhibitor.
  10. Go6893, PKC Inhibitor

    Catalog No. M60273
    A potent pan-PKC inhibitor.
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