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Anti-cancer

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  1. Nocodazole, Microtubule Inhibitor / CRISPR Editing Enhancer

    $79.00
    Catalog No. M60331
    A potent microtubule inhibitor to inhibit mitosis and CRISPR editing enhancer.
  2. (+)-JQ1, BET Inhibitor

    $109.00   $139.00
    Catalog No. M60139
    A potent and selective inhibitor of the bromodomain and extra terminal (BET) family proteins BRD2, BRD3, and BRD4
  3. (R)-2-HG, a-KG-dependent dioxygenases inhibitor

    $69.00
    Catalog No. M60104
    An a-KG-dependent dioxygenases inhibitor
  4. (S)-crizotinib, MTH1 Inhibitor

    $99.00
    Catalog No. M60208
    A novel potent, selective and cell permeable MTH1 inhibitor.
  5. (Z)-4-Hydroxytamoxifen, CRISPR Editing Enhancer

    $89.00
    Catalog No. M60324
    Previously characterized as an Estrogen Receptor antagonist and now found to improve genome-editing specificity in CRISPR-mediated gene editing
  6. 1-methyl-D-tryptophan (D-1MT), IDO Inhibitor

    $29.00
    Catalog No. M60291
    A potent and selective indoleamine 2,3-dioxygenase (IDO) inhibitor.
  7. 4SC-202, HDAC/LSD1 Dual Inhibitor

    $109.00
    Catalog No. M60230
    A potent, selective and orally bioavailable HDAC/LSD1 dual Inhibitor.
  8. 5-Azacytidine, DNA Methyltransferase Inhibitor

    $59.00
    Catalog No. M60131
    A classic DNA methyltransferase inhibitor, incorporates into DNA forming covalent adducts with cellular DNMT, depleting enzyme activity.
  9. A-366, G9a/GLP HMTase Inhibitor

    $139.00
    Catalog No. M60210
    A novel highly potent, selective and cell permeable G9a/GLP histone lysine methyltransferase inhibitor.
  10. A01, Smurf1 E3 Ubiquitin Ligase Inhibitor

    $109.00
    Catalog No. M60249
    A potent and selective Smurf1 E3 ubiquitin ligase inhibitor.
  11. AA92593, Antagonist of Melanopsin-mediated Photo-transduction

    $139.00
    Catalog No. M60143
    A potent and selective small molecule antagonist of melanopsin-mediated photo-transduction.
  12. Abiraterone, CYP17 inhibitor Abiraterone (CB-7598)

    $69.00
    Catalog No. M60031
    A first-in-class CYP17 inhibitor approved to treat castration-resistant prostate cancer.
  13. ABT-199, BCL-2 inhibitor

    $99.00
    Catalog No. M60075
    A potent BCL-2–selective (BCL-X L) inhibitor with clinical efficacy.
  14. AG-120 (Ivosidenib), IDH1 Inhibitor

    $129.00
    Catalog No. M60318
    A potent, selective and reversible inhibitor of IDH1 in clinical trials.
  15. AG-221 (Enasidenib), IHD2 Inhibitor

    $129.00
    Catalog No. M60296
    A potent and selective inhibitor of IDH2 R140Q mutant.
  16. APY29, IRE1a Modulator

    $109.00
    Catalog No. M60168
    A highly potent and selective small molecule modulator of IRE1α.
  17. AS8351, KDM5B Inhibitor

    $109.00
    Catalog No. M60330
    A potent iron chelator that has been found to inhibit of histone demethylase KDM5B (JARID1B).
  18. AZD6244 (Selumetinib), MEK Inhibitor

    $109.00
    Catalog No. M60067
    A potent and highly selective non-ATP competitive MEK inhibitor in clinical trials.
  19. Azidothymidine (AZT), Reverse Transcriptase Inhibitor

    $29.00
    Catalog No. M60238
    A selective, orally bioavailable and brain penetrant reverse transcriptase inhibitor.
  20. b-AP15 (NSC687852), Deubiquitinases Inhibitor

    $89.00
    Catalog No. M60251
    A potent and selective deubiquitinases inhibitor for 19S proteasomes activity of Ub-AMC cleavage.
  21. BAM7, BAX Activator

    $109.00
    Catalog No. M60069
    The first potent and selective small molecule activator of BAX, which is a pro-apoptotic BCL-2 family member.
  22. BAY 87-2243, Hypoxia-inducible Factor-1 (HIF-1) Inhibitor

    $119.00
    Catalog No. M60217
    A highly potent and selective hypoxia-inducible factor-1 (HIF-1) inhibitor.
  23. BAY11-7082, E2 Ubiquitin Conjugating Enzyme Inhibitor

    $89.00
    Catalog No. M60309
    A potent and selective E2 ubiquitin (Ub) conjugating enzyme inhibitor.
  24. BG45, HDAC3 Inhibitor

    $59.00
    Catalog No. M60266
    A potent, selective and cell permeable HDAC3 inhibitor.
  25. BI-2536, PLK1 and BRD4 Dual Inhibitor

    $119.00
    Catalog No. M60171
    BI-2536 is a potent inhibitor of PLK1 (Polo-like kinase 1) and BRD4 in clinical trials.
  26. BI-7273, BRD9 Bromodomain Inhibitor

    $129.00
    Catalog No. M60322
    A potent, selective and cell-permeable BRD9 inhibitor.
  27. BI-9564, BRD9 Bromodomain Inhibitor

    $129.00
    Catalog No. M60323
    A potent, selective and cell-permeable BRD9 inhibitor.
  28. BIBW2992(Afatinib), EGFR Inhibitor

    $109.00
    Catalog No. M60065-5s
    A potent and selective irreversible inhibitor of EGFR/HER2 in clinical trials.
  29. Bioymifi, TRAIL Receptor DR5 Activator

    $109.00
    Catalog No. M60088
    A potent and selective small molecule agonist of DR5.
  30. BIX-01294, G9a/GLP HMTase Inhibitor

    $79.00
    Catalog No. M60216
    A potent and selective G9a and GLP histone lysine methyltransferase inhibitor.
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