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Anti-diabetic

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  1. SR9011, REV-ERB Agonist

    $109.00
    Catalog No. M66049
    A potent synthetic REV-ERB agonist with in vivo activity; can regulate circadian behavior and metabolism.
  2. SR1664,PPAR-γ Modulator

    $109.00
    Catalog No. M66048
    An unique PPARγ modulator that has potent anti-diabetic activity through blocking the Cdk5-mediated phosphorylation of PPARγ, but completely lacks classical transcriptional agonism that accounts for other PPARγ agonists’ side effects.
  3. INDY, DYRK1A/B Inhibitor

    $79.00
    Catalog No. M60242
    A potent and selective DYRK1A/B inhibitor.
  4. Harmine, DYRK1A Inhibitor

    $29.00
    Catalog No. M60241
    A potent, selective and orally bioavailable DYRK1A inhibitor.
  5. AS2034178, GPR40 Agonist

    $139.00
    Catalog No. M60221
    A potent, selective and orally bioavailable GPR40 (FFA1) agonist.
  6. TAK-875 (Fasiglifam), GPR40 Agonist

    $139.00
    Catalog No. M60220
    A potent, selective and orally bioavailable partial GPR40 agonist.
  7. GPR39-C3, GPR39 Agonist

    $139.00
    Catalog No. M60209
    The first potent, selective and orally bioavailable GPR39 agonist.
  8. P5091, Ubiquitin-specific Protease 7 (USP7) Inhibitor

    $79.00
    Catalog No. M60205
    P5091 (P005091) is a novel potent and selective inhibitor of ubiquitin-specific protease 7 (USP7)
  9. BETP, GLP-1R Potentiator

    $129.00
    Catalog No. M60196
    A positive allosteric modulator and partial agonist of the glucagon-like peptide 1 (GLP-1) receptor.
  10. Fatostatin A, Sterol Regulatory Binding Proteins (SREBPs) Inhibitor

    $59.00
    Catalog No. M60180
    Fatostatin A is a highly potent, specific and cell permeable inhibitor of Sterol Regulatory Binding Proteins (SREBPs).
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