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BMI1 Mouse Monoclonal Antibody

BMI1 Mouse Monoclonal Antibody

$0.00
BMI1 Mouse Monoclonal Antibody.
Catalog No. Unit Price Qty
A90010-b Bulk Request $0.00
A90010-5 5ug $0.00

Details

Product Information

Clonality: Monoclonal Source: Mouse    
Detected band  (by western) MW: 37 KD Cross-Reactivity: Human    
Concentration: 100 ug/100 ul      
Applications: ELISA 1/10000, WB 1/500 - 1/2000, IHC 1/200 - 1/1000, ICC 1/200 - 1/1000, FCM 1/200 - 1/400  
         

Alt. Names

H3 histone antibody, HIST1H3A antibody, Histone cluster 1, H3a antibody

Specificity:

BMI1 antibody detects endogenous levels of total BMI1

Immunogen:

Purified recombinant fragment of human BMI1 expressed in E. Coli

Purification:

Affinity-chromatography

Storage Condition and Buffer:

Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.


Background:

Polycomb complex protein BMI-1 is found a canonical self-renewal regulator. Tumor Formation and, more specifically, human colorectal cancer-initiating cells (CIC) are dependent on BMI-1.  Down-regulation of BMI-1 inhibits the ability of colorectal CICs to self-renew, resulting in the abrogation of their tumorigenic potential.  Targeting the BMI-1 self-renewal machinery represents a promising approach to the elimination of many cancer stem (and initiating) cells. 

BIMI-1 antibody detects endogenous levels of total BMI-1, thus a good tool of BMI-1 related cancer study.

Please refer PDF file for Western, Immunofluorescence analysis,Chromatin immunoprecipitation analysis or other QC data.

PDF:

BMI1_monocolonal_Antibody

SDS:

SDS_BMI1_mouse_monoclonal_antibody_.pdf

Reference:

  1. Kreso A, et al.  Self-renewal as a therapeutic target in human colorectal cancer. (2014) Nat Med. (1):29-36. 


Product is for research use only. Not for human use.

Description

Details

Product Information

Clonality: Monoclonal Source: Mouse    
Detected band  (by western) MW: 37 KD Cross-Reactivity: Human    
Concentration: 100 ug/100 ul      
Applications: ELISA 1/10000, WB 1/500 - 1/2000, IHC 1/200 - 1/1000, ICC 1/200 - 1/1000, FCM 1/200 - 1/400  
         

Alt. Names

H3 histone antibody, HIST1H3A antibody, Histone cluster 1, H3a antibody

Specificity:

BMI1 antibody detects endogenous levels of total BMI1

Immunogen:

Purified recombinant fragment of human BMI1 expressed in E. Coli

Purification:

Affinity-chromatography

Storage Condition and Buffer:

Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.


Background:

Polycomb complex protein BMI-1 is found a canonical self-renewal regulator. Tumor Formation and, more specifically, human colorectal cancer-initiating cells (CIC) are dependent on BMI-1.  Down-regulation of BMI-1 inhibits the ability of colorectal CICs to self-renew, resulting in the abrogation of their tumorigenic potential.  Targeting the BMI-1 self-renewal machinery represents a promising approach to the elimination of many cancer stem (and initiating) cells. 

BIMI-1 antibody detects endogenous levels of total BMI-1, thus a good tool of BMI-1 related cancer study.

Please refer PDF file for Western, Immunofluorescence analysis,Chromatin immunoprecipitation analysis or other QC data.

PDF:

BMI1_monocolonal_Antibody

SDS:

SDS_BMI1_mouse_monoclonal_antibody_.pdf

Reference:

  1. Kreso A, et al.  Self-renewal as a therapeutic target in human colorectal cancer. (2014) Nat Med. (1):29-36. 


Product is for research use only. Not for human use.

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