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Epigenetic targets

Comprehensive Unique Epigenetics Probes Collection

Need the best set of epigenetics probes to test your hypothesis in cancers, inflammation, or other diseases and phenotypes entailed with epigenetic regulation? Xcess Biosciences offers the comprehensive unique collection of highly potent and selective epigenetics modulators with the best in vitro and in vivo properties to facilitate your research.

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  1. (+)-JQ1, BET Inhibitor

    $109.00   $139.00
    Catalog No. M60139
    A potent and selective inhibitor of the bromodomain and extra terminal (BET) family proteins BRD2, BRD3, and BRD4
  2. (R)-2-HG, a-KG-dependent dioxygenases inhibitor

    $69.00
    Catalog No. M60104
    An a-KG-dependent dioxygenases inhibitor
  3. 1,4-DPCA, Prolyl 4-hydroxylase (P4H) Inhibitor

    $29.00
    Catalog No. M60288
    A selective and cell permeable prolyl 4-hydroxylase (P4H) inhibitor.
  4. 4SC-202, HDAC/LSD1 Dual Inhibitor

    $109.00
    Catalog No. M60230
    A potent, selective and orally bioavailable HDAC/LSD1 dual Inhibitor.
  5. 5-Azacytidine, DNA Methyltransferase Inhibitor

    $59.00
    Catalog No. M60131
    A classic DNA methyltransferase inhibitor, incorporates into DNA forming covalent adducts with cellular DNMT, depleting enzyme activity.
  6. A-366, G9a/GLP HMTase Inhibitor

    $139.00
    Catalog No. M60210
    A novel highly potent, selective and cell permeable G9a/GLP histone lysine methyltransferase inhibitor.
  7. ACY-1215 (Rocilinostat), HDAC6 inhibitor

    $109.00
    Catalog No. M60076
    A highly potent, selective, and orally bioavailable inhibitor of histone deacetylase 6 (HDAC6).
  8. AG-120 (Ivosidenib), IDH1 Inhibitor

    $129.00
    Catalog No. M60318
    A potent, selective and reversible inhibitor of IDH1 in clinical trials.
  9. AG-221 (Enasidenib), IHD2 Inhibitor

    $129.00
    Catalog No. M60296
    A potent and selective inhibitor of IDH2 R140Q mutant.
  10. AGI-5198 (IDH-C35), Mutant IDH1 Inhibitor

    $109.00
    Catalog No. M60068
    The first highly potent and selective mutant IDH1 inhibitor that was shown to have anti-tumor efficacy in vivo.
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