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Epigenetic targets

Comprehensive Unique Epigenetics Probes Collection

Need the best set of epigenetics probes to test your hypothesis in cancers, inflammation, or other diseases and phenotypes entailed with epigenetic regulation? Xcess Biosciences offers the comprehensive unique collection of highly potent and selective epigenetics modulators with the best in vitro and in vivo properties to facilitate your research.

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  1. AGI-6780, Mutant IDH2 Inhibitor

    Catalog No. M60105
    The first highly potent and selective small molecule mutant IDH2 inhibitor.
  2. AK-7, SIRT2 Inhibitor

    Catalog No. M60107
    A cell- and brain-permeable, selective sirtuin SIRT2 inhibitor, displays no effect on SIRT1 or SIRT3.
  3. AMI-1, Histone Methyltransferase Inhibitor

    Catalog No. M60272
    A potent and specific small molecule inhibitor of histone methyltransferase targeting yeast Hmt1p and human PRMT1.
  4. AS8351, KDM5B Inhibitor

    Catalog No. M60330
    A potent iron chelator that has been found to inhibit of histone demethylase KDM5B (JARID1B).
  5. BAY 87-2243, Hypoxia-inducible Factor-1 (HIF-1) Inhibitor

    Catalog No. M60217
    A highly potent and selective hypoxia-inducible factor-1 (HIF-1) inhibitor.
  6. BAZ2-ICR, BAZ2 Bromodomain Inhibitor

    Catalog No. M60226
    A potent and selective BAZ2 bromodomain inhibitor.
  7. BG45, HDAC3 Inhibitor

    Catalog No. M60266
    A potent, selective and cell permeable HDAC3 inhibitor.
  8. BI-2536, PLK1 and BRD4 Dual Inhibitor

    Catalog No. M60171
    BI-2536 is a potent inhibitor of PLK1 (Polo-like kinase 1) and BRD4 in clinical trials.
  9. BI-7273, BRD9 Bromodomain Inhibitor

    Catalog No. M60322
    A potent, selective and cell-permeable BRD9 inhibitor.
  10. BI-9564, BRD9 Bromodomain Inhibitor

    Catalog No. M60323
    A potent, selective and cell-permeable BRD9 inhibitor.
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