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Epigenetic targets

Comprehensive Unique Epigenetics Probes Collection

Need the best set of epigenetics probes to test your hypothesis in cancers, inflammation, or other diseases and phenotypes entailed with epigenetic regulation? Xcess Biosciences offers the comprehensive unique collection of highly potent and selective epigenetics modulators with the best in vitro and in vivo properties to facilitate your research.

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  1. CUDC-907, PI3K/HDAC dual inhibitor

    $139.00
    Catalog No. M60077
    A potent dual inhibitor of class I PI3K kinases and HDACs in clinical trials.
  2. Daminozide --- KDM2/7 Histone Demethylases Inhibitor

    $69.00
    Catalog No. M60074
    A potent and selective small molecule inhibitor of the KDM2/7 family of human JmjC histone demethylases.
  3. DMOG, Prolyl 4-hydroxylase (P4H) Inhibitor

    $39.00
    Catalog No. M60287
    A selective, competitive and cell permeable prolyl 4-hydroxylase (P4H) inhibitor.
  4. DZNep (3-Deazaneplanocin A) --- Histone Methyltransferase Inhibitor

    $129.00
    Catalog No. M60141
    An S-adenosylhomocysteine hydrolase inhibitor, indirectly inhibiting histone methyltransferases and decreasing global DNA methylation
  5. EED226, PRC2 Inhibitor

    $139.00
    Catalog No. M60327
    A potent and selective allosteric PRC2 inhibitor that directly binds to the H3K27me3 binding pocket of EED.
  6. EML425, CBP/p300 Inhibitor

    $129.00
    Catalog No. M60257
    A selective, noncompetitive and cell permeable KAT3 histone acetyltransferases CBP/p300 inhibitor.
  7. Entinostat (MS-275) -- HDAC Inhibitor

    $59.00
    Catalog No. M60174
    Entinostat (MS-275) is a potent and selective HDAC1 and HDAC3 inhibitor.
  8. EPZ-5676 --- DOT1L inhibitor

    $139.00
    Catalog No. M60123
    A highly potent and selective inhibitor of DOT1L methyltransferase with Ki of 70 pM, selectively blocking the binding of the cofactor, S-adenosylmethionine.
  9. EPZ-6438, EZH2 Methyltransferase Inhibitor

    $129.00
    Catalog No. M60122
    EPZ-6438 (E7438) is a potent and selective small molecule inhibitor of histone methyltransferase EZH2 in clinical development.
  10. EPZ015666 (GSK3235025), PRMT5 Inhibitor

    $129.00
    Catalog No. M60254
    A potent, selective and orally bioavailable Protein arginine methyltransferase-5 (PRMT5) Inhibitor.
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