Comprehensive Unique Epigenetics Probes Collection
Need the best set of epigenetics probes to test your hypothesis in cancers, inflammation, or other diseases and phenotypes entailed with epigenetic regulation? Xcess Biosciences offers the comprehensive unique collection of highly potent and selective epigenetics modulators with the best in vitro and in vivo properties to facilitate your research.
Catalog No. M60077
A potent dual inhibitor of class I PI3K kinases and HDACs in clinical trials.
Catalog No. M60074
A potent and selective small molecule inhibitor of the KDM2/7 family of human JmjC histone demethylases.
Catalog No. M60287
A selective, competitive and cell permeable prolyl 4-hydroxylase (P4H) inhibitor.
Catalog No. M60141
An S-adenosylhomocysteine hydrolase inhibitor, indirectly inhibiting histone methyltransferases and decreasing global DNA methylation
Catalog No. M60327
A potent and selective allosteric PRC2 inhibitor that directly binds to the H3K27me3 binding pocket of EED.
Catalog No. M60257
A selective, noncompetitive and cell permeable KAT3 histone acetyltransferases CBP/p300 inhibitor.
Catalog No. M60174
Entinostat (MS-275) is a potent and selective HDAC1 and HDAC3 inhibitor.
Catalog No. M60123
A highly potent and selective inhibitor of DOT1L methyltransferase with Ki of 70 pM, selectively blocking the binding of the cofactor, S-adenosylmethionine.
Catalog No. M60122
EPZ-6438 (E7438) is a potent and selective small molecule inhibitor of histone methyltransferase EZH2 in clinical development.
Catalog No. M60254
A potent, selective and orally bioavailable Protein arginine methyltransferase-5 (PRMT5) Inhibitor.