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Epigenetic targets

Comprehensive Unique Epigenetics Probes Collection

Need the best set of epigenetics probes to test your hypothesis in cancers, inflammation, or other diseases and phenotypes entailed with epigenetic regulation? Xcess Biosciences offers the comprehensive unique collection of highly potent and selective epigenetics modulators with the best in vitro and in vivo properties to facilitate your research.

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  1. EX-527, SIRT1 Inhibitor

    $69.00
    Catalog No. M60108
    EX-527 is a highly potent and selective inhibitor of SIRT1 with an IC50 ~98 nM.
  2. FG-4592 (Roxadustat), HIF Prolyl-Hydroxylases Inhibitor

    $39.00
    Catalog No. M60263
    A potent, selective and bioavailable inhibitor of hypoxia-inducible factor prolyl hydroxylase.
  3. Furamidine, PRMT1 Inhibitor

    $99.00
    Catalog No. M60256
    A potent, selective and cell permeable Protein arginine methyltransferase-1 (PRMT1) inhibitor.
  4. GN44028, HIF-1α Inhibitor

    $89.00
    Catalog No. M60325
    A potent and selective HIF-1α inhibitor.
  5. GSK-J1, H3K27 Histone Demethylases UTX and JMJD3 Inhibitor

    $109.00
    Catalog No. M60062
    The first selective and potent inhibitor of the H3K27 histone demethylases UTX and JMJD3.
  6. GSK-J4, H3K27 Histone Demethylases UTX and JMJD3 Inhibitor

    $109.00
    Catalog No. M60063
    An ethyl ester derivative of GSK-J1 as a pro-drug for cellular assays; the first selective and potent inhibitor of the H3K27 histone demethylases UTX and JMJD3.
  7. GSK-LSD1, LSD1 Inhibitor

    $139.00
    Catalog No. M60179
    A highly potent, specific and irreversible inhibitor of Lysine Specific Demethylase-1 (LSD1).
  8. GSK126, EZH2 Methyltransferase Inhibitor.

    $129.00
    Catalog No. M60071
    GSK126 is a highly potent and selective small molecule inhibitor of histone methyltransferase EZH2.
  9. GSK2801, Bromodomain BAZ2A/B Inhibitor

    $129.00
    Catalog No. M60283
    A potent, selective and cell permeable inhibitor of the bromodomain BAZ2A and BAZ2B.
  10. GSK2879552, LSD1 Inhibitor

    $129.00
    Catalog No. M60297
    A highly potent, selective and orally bioavailable irreversible inhibitor of Lysine Specific Demethylase 1 (LSD1).
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