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Epigenetic targets

Comprehensive Unique Epigenetics Probes Collection

Need the best set of epigenetics probes to test your hypothesis in cancers, inflammation, or other diseases and phenotypes entailed with epigenetic regulation? Xcess Biosciences offers the comprehensive unique collection of highly potent and selective epigenetics modulators with the best in vitro and in vivo properties to facilitate your research.

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  1. KDM5-C70, JARID1 Histone Demethylases Inhibitor

    Catalog No. M60192
    An ethyl ester derivative of KDM5-C49, which is a potent and selective inhibitor of Jumonji AT-Rich Interactive Domain 1 (JARID1) histone demethylases.
  2. L002 (NSC764414), p300 Inhibitor

    Catalog No. M60198
    A novel selective, cell permeable and reversible inhibitor of p300 histone acetyl transferase.
  3. LLY-507, Protein-lysine Methyltransferase SMYD2 Inhibitor

    Catalog No. M60259
    A potent, selective and cell permeable protein lysine methyltransferase SMYD2 inhibitor.
  4. LMK235, HDAC4 and HDAC5 Inhibitor

    Catalog No. M60145
    A potent and selective histone deacetylase HDAC4 and HDAC5 inhibitor.
  5. LSD1-C76, LSD1 Inhibitor

    Catalog No. M66045
    The most potent and selective Lysine Specific Demethylase-1 (LSD1) inhibitor so far.
  6. LY294002, PI3K/BET Dual Inhibitor

    Catalog No. M60157
    A potent and selective small molecule PI3K and BET bromodomain dual inhibitor.
  7. MC1568, Class IIa HDAC Inhibitor

    Catalog No. M60224
    A potent and selective inhibitor of class IIa histone deacetylases (HDACs), more selective for HD1-A than HD1-B.
  8. MI-2, Menin-MLL Inhibitor

    Catalog No. M66046
    A highly potent and selective small molecule directly binding to MALT1 and irreversibly suppressing its protease function.
  9. ML228, HIF Pathway Activator

    Catalog No. M60130
    A potent and selective hypoxia inducible factor (HIF) pathway activator.
  10. ML324, JMJD2 Histone Demethylase Inhibitor

    Catalog No. M60183
    A potent, selective and cell permeable inhibitor of Jumonji domain-containing protein 2 (JMJD2) histone demethylase.
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