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Epigenetic targets

Comprehensive Unique Epigenetics Probes Collection

Need the best set of epigenetics probes to test your hypothesis in cancers, inflammation, or other diseases and phenotypes entailed with epigenetic regulation? Xcess Biosciences offers the comprehensive unique collection of highly potent and selective epigenetics modulators with the best in vitro and in vivo properties to facilitate your research.

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  1. (+)-JQ1, BET Inhibitor

    $109.00   $139.00
    Catalog No. M60139
    A potent and selective inhibitor of the bromodomain and extra terminal (BET) family proteins BRD2, BRD3, and BRD4
  2. (R)-2-HG, a-KG-dependent dioxygenases inhibitor

    $69.00
    Catalog No. M60104
    An a-KG-dependent dioxygenases inhibitor
  3. 1,4-DPCA, Prolyl 4-hydroxylase (P4H) Inhibitor

    $29.00
    Catalog No. M60288
    A selective and cell permeable prolyl 4-hydroxylase (P4H) inhibitor.
  4. 4SC-202, HDAC/LSD1 Dual Inhibitor

    $109.00
    Catalog No. M60230
    A potent, selective and orally bioavailable HDAC/LSD1 dual Inhibitor.
  5. 5-Azacytidine, DNA Methyltransferase Inhibitor

    $59.00
    Catalog No. M60131
    A classic DNA methyltransferase inhibitor, incorporates into DNA forming covalent adducts with cellular DNMT, depleting enzyme activity.
  6. A-366, G9a/GLP HMTase Inhibitor

    $139.00
    Catalog No. M60210
    A novel highly potent, selective and cell permeable G9a/GLP histone lysine methyltransferase inhibitor.
  7. ACY-1215 (Rocilinostat), HDAC6 inhibitor

    $109.00
    Catalog No. M60076
    A highly potent, selective, and orally bioavailable inhibitor of histone deacetylase 6 (HDAC6).
  8. AG-120 (Ivosidenib), IDH1 Inhibitor

    $129.00
    Catalog No. M60318
    A potent, selective and reversible inhibitor of IDH1 in clinical trials.
  9. AG-221 (Enasidenib), IHD2 Inhibitor

    $129.00
    Catalog No. M60296
    A potent and selective inhibitor of IDH2 R140Q mutant.
  10. AGI-5198 (IDH-C35), Mutant IDH1 Inhibitor

    $109.00
    Catalog No. M60068
    The first highly potent and selective mutant IDH1 inhibitor that was shown to have anti-tumor efficacy in vivo.
  11. AGI-6780, Mutant IDH2 Inhibitor

    $109.00
    Catalog No. M60105
    The first highly potent and selective small molecule mutant IDH2 inhibitor.
  12. AK-7, SIRT2 Inhibitor

    $69.00
    Catalog No. M60107
    A cell- and brain-permeable, selective sirtuin SIRT2 inhibitor, displays no effect on SIRT1 or SIRT3.
  13. AMI-1, Histone Methyltransferase Inhibitor

    $79.00
    Catalog No. M60272
    A potent and specific small molecule inhibitor of histone methyltransferase targeting yeast Hmt1p and human PRMT1.
  14. AS8351, KDM5B Inhibitor

    $109.00
    Catalog No. M60330
    A potent iron chelator that has been found to inhibit of histone demethylase KDM5B (JARID1B).
  15. BAY 87-2243, Hypoxia-inducible Factor-1 (HIF-1) Inhibitor

    $119.00
    Catalog No. M60217
    A highly potent and selective hypoxia-inducible factor-1 (HIF-1) inhibitor.
  16. BAZ2-ICR, BAZ2 Bromodomain Inhibitor

    $129.00
    Catalog No. M60226
    A potent and selective BAZ2 bromodomain inhibitor.
  17. BG45, HDAC3 Inhibitor

    $59.00
    Catalog No. M60266
    A potent, selective and cell permeable HDAC3 inhibitor.
  18. BI-2536, PLK1 and BRD4 Dual Inhibitor

    $119.00
    Catalog No. M60171
    BI-2536 is a potent inhibitor of PLK1 (Polo-like kinase 1) and BRD4 in clinical trials.
  19. BI-7273, BRD9 Bromodomain Inhibitor

    $129.00
    Catalog No. M60322
    A potent, selective and cell-permeable BRD9 inhibitor.
  20. BI-9564, BRD9 Bromodomain Inhibitor

    $129.00
    Catalog No. M60323
    A potent, selective and cell-permeable BRD9 inhibitor.
  21. BIX-01294, G9a/GLP HMTase Inhibitor

    $79.00
    Catalog No. M60216
    A potent and selective G9a and GLP histone lysine methyltransferase inhibitor.
  22. BRD9757, HDAC6 Inhibitor

    $129.00
    Catalog No. M60117
    A highly potent and selective HDAC6 inhibitor.
  23. Bromosporine, Pan-bromodomain Inhibitor

    $129.00
    Catalog No. M60144
    A broad spectrum inhibitor for bromodomains.
  24. C646, p300/CBP inhibitor

    $129.00
    Catalog No. M60129
    A potent, selective and cell-permeable p300/CBP histone acetyltransferase (HAT) inhibitor.
  25. CAY10603, HDAC6 Inhibitor

    $129.00
    Catalog No. M60234
    A potent and selective HDAC6 inhibitor.
  26. CI994 (Tacedinaline), HDAC Inhibitor

    $59.00
    Catalog No. M60186
    A potent, selective and orally active histone deacetylase (HDAC) inhibitor targeting HDAC1, HDAC2 and HDAC3.
  27. CPI-169, EZH2 Methyltransferase Inhibitor

    $129.00
    Catalog No. M60275
    A highly potent and selective small molecule inhibitor of histone methyltransferase EZH2.
  28. CPI-455, KDM5 Demethylases Inhibitor

    $129.00
    Catalog No. M60326
    A potent and selective KDM5A inhibitor.
  29. CPI203, BET Inhibitor

    $139.00
    Catalog No. M60124
    A novel potent, selective and cell permeable inhibitor of the bromodomain and extra terminal (BET) family protein BRD4, inhibiting Myc expression.
  30. CUDC-101, HDAC/EGFR/HER2 Inhibitor

    $69.00
    Catalog No. M60092
    A potent multi-target inhibitor targeting HDAC, EGFR and HER2 in clinical trial.
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