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Epigenetic targets

Comprehensive Unique Epigenetics Probes Collection

Need the best set of epigenetics probes to test your hypothesis in cancers, inflammation, or other diseases and phenotypes entailed with epigenetic regulation? Xcess Biosciences offers the comprehensive unique collection of highly potent and selective epigenetics modulators with the best in vitro and in vivo properties to facilitate your research.

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  1. UNC0638, G9a HMTase Inhibitor

    Catalog No. M66056
    A potent, selective and cell permeable inhibitor of G9a (EHMT2) and GLP (EHMT1) histone methyltransferases.
  2. IOX2, HIF Prolyl-Hydroxylases (PHD2) Inhibitor

    Catalog No. M66054
    A potent and selective PHD (HIF prolyl-hydroxylases) inhibitor with cellular activity.
  3. I-BET151 (GSK1210151A), BET Inhibitor

    Catalog No. M66053
    A potent and selective inhibitor of the bromodomain and extra terminal (BET) family proteins BRD2, BRD3, and BRD4.
  4. MI-2, Menin-MLL Inhibitor

    Catalog No. M66046
    A highly potent and selective small molecule directly binding to MALT1 and irreversibly suppressing its protease function.
  5. LSD1-C76, LSD1 Inhibitor

    Catalog No. M66045
    The most potent and selective Lysine Specific Demethylase-1 (LSD1) inhibitor so far.
  6. AS8351, KDM5B Inhibitor

    Catalog No. M60330
    A potent iron chelator that has been found to inhibit of histone demethylase KDM5B (JARID1B).
  7. EED226, PRC2 Inhibitor

    Catalog No. M60327
    A potent and selective allosteric PRC2 inhibitor that directly binds to the H3K27me3 binding pocket of EED.
  8. CPI-455, KDM5 Demethylases Inhibitor

    Catalog No. M60326
    A potent and selective KDM5A inhibitor.
  9. GN44028, HIF-1α Inhibitor

    Catalog No. M60325
    A potent and selective HIF-1α inhibitor.
  10. BI-9564, BRD9 Bromodomain Inhibitor

    Catalog No. M60323
    A potent, selective and cell-permeable BRD9 inhibitor.
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