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Epigenetic targets

Comprehensive Unique Epigenetics Probes Collection

Need the best set of epigenetics probes to test your hypothesis in cancers, inflammation, or other diseases and phenotypes entailed with epigenetic regulation? Xcess Biosciences offers the comprehensive unique collection of highly potent and selective epigenetics modulators with the best in vitro and in vivo properties to facilitate your research.

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  1. LSD1-C76, LSD1 Inhibitor

    Catalog No. M66045
    The most potent and selective Lysine Specific Demethylase-1 (LSD1) inhibitor so far.
  2. CUDC-907, PI3K/HDAC dual inhibitor

    Catalog No. M60077
    A potent dual inhibitor of class I PI3K kinases and HDACs in clinical trials.
  3. CPI203, BET Inhibitor

    Catalog No. M60124
    A novel potent, selective and cell permeable inhibitor of the bromodomain and extra terminal (BET) family protein BRD4, inhibiting Myc expression.
  4. EPZ-5676 --- DOT1L inhibitor

    Catalog No. M60123
    A highly potent and selective inhibitor of DOT1L methyltransferase with Ki of 70 pM, selectively blocking the binding of the cofactor, S-adenosylmethionine.
  5. PFI-2, SETD7 Histone Lysine Methyltransferase Inhibitor

    Catalog No. M60182
    PFI-2 is a novel potent and selective SETD7 histone lysine methyltransferase inhibitor.
  6. PFI-3, SMARCA Bromodomains Inhibitor

    Catalog No. M60175
    PFI-3 is a novel potent, selective and cell permeable inhibitor of SMARCA4 and PB1(5) bromodomains.
  7. GSK-LSD1, LSD1 Inhibitor

    Catalog No. M60179
    A highly potent, specific and irreversible inhibitor of Lysine Specific Demethylase-1 (LSD1).
  8. HIF-C2, HIF-2 Inhibitor

    Catalog No. M60121
    A potent and selective allosteric inhibitor of hypoxia inducible factor-2 (HIF-2).
  9. I-BET762 (GSK525762), BET Inhibitor

    Catalog No. M60154
    A novel, highly potent, selective and cell permeable BET inhibitor in clinical trials.
  10. I-CBP112, p300/CBP Bromodomain Inhibitor

    Catalog No. M60128
    A highly potent and selective p300/CBP bromodomain inhibitor.
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