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Histone Methyltransferase

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  1. A-366, G9a/GLP HMTase Inhibitor

    $139.00
    Catalog No. M60210
    A novel highly potent, selective and cell permeable G9a/GLP histone lysine methyltransferase inhibitor.
  2. AMI-1, Histone Methyltransferase Inhibitor

    $79.00
    Catalog No. M60272
    A potent and specific small molecule inhibitor of histone methyltransferase targeting yeast Hmt1p and human PRMT1.
  3. BIX-01294, G9a/GLP HMTase Inhibitor

    $79.00
    Catalog No. M60216
    A potent and selective G9a and GLP histone lysine methyltransferase inhibitor.
  4. CPI-169, EZH2 Methyltransferase Inhibitor

    $129.00
    Catalog No. M60275
    A highly potent and selective small molecule inhibitor of histone methyltransferase EZH2.
  5. DZNep (3-Deazaneplanocin A) --- Histone Methyltransferase Inhibitor

    $129.00
    Catalog No. M60141
    An S-adenosylhomocysteine hydrolase inhibitor, indirectly inhibiting histone methyltransferases and decreasing global DNA methylation
  6. EPZ-5676 --- DOT1L inhibitor

    $139.00
    Catalog No. M60123
    A highly potent and selective inhibitor of DOT1L methyltransferase with Ki of 70 pM, selectively blocking the binding of the cofactor, S-adenosylmethionine.
  7. EPZ-6438, EZH2 Methyltransferase Inhibitor

    $129.00
    Catalog No. M60122
    EPZ-6438 (E7438) is a potent and selective small molecule inhibitor of histone methyltransferase EZH2 in clinical development.
  8. EPZ015666 (GSK3235025), PRMT5 Inhibitor

    $129.00
    Catalog No. M60254
    A potent, selective and orally bioavailable Protein arginine methyltransferase-5 (PRMT5) Inhibitor.
  9. Furamidine, PRMT1 Inhibitor

    $99.00
    Catalog No. M60256
    A potent, selective and cell permeable Protein arginine methyltransferase-1 (PRMT1) inhibitor.
  10. GSK126, EZH2 Methyltransferase Inhibitor.

    $129.00
    Catalog No. M60071
    GSK126 is a highly potent and selective small molecule inhibitor of histone methyltransferase EZH2.
  11. GSK343, EZH2 Methyltransferase Inhibitor

    $79.00
    Catalog No. M60173
    GSK343 is a potent and selective small molecule inhibitor of histone methyltransferase EZH2.
  12. GSK591 (EPZ015866), PRMT5 Inhibitor

    $109.00
    Catalog No. M60321
    A potent and selective Protein arginine methyltransferase-5 (PRMT5) Inhibitor.
  13. HLCL-61, PRMT5 Inhibitor

    $109.00
    Catalog No. M60320
    A potent and selective Protein arginine methyltransferase-5 (PRMT5) Inhibitor.
  14. LLY-507, Protein-lysine Methyltransferase SMYD2 Inhibitor

    $129.00
    Catalog No. M60259
    A potent, selective and cell permeable protein lysine methyltransferase SMYD2 inhibitor.
  15. MS023, PRMT Inhibitor

    $109.00
    Catalog No. M60314
    A potent, selective and cell permeable type I PRMT inhibitor.
  16. MS049, PRMT4 and PRMT6 Inhibitor

    $89.00
    Catalog No. M60310
    A potent, selective and cell permeable PRMT4 and PRMT6 inhibitor.
  17. PFI-2, SETD7 Histone Lysine Methyltransferase Inhibitor

    $139.00
    Catalog No. M60182
    PFI-2 is a novel potent and selective SETD7 histone lysine methyltransferase inhibitor.
  18. PRMT1-2e, Protein Arginine Methyltransferase 1 (PRMT1) Inhibitor

    $69.00
    Catalog No. M60181
    PRMT1-2e is a potent, specific and cell permeable inhibitor of protein arginine methyltransferase 1 (PRMT1).
  19. Ryuvidine, Lysine Methyltransferase SETD8 Inhibitor

    $129.00
    Catalog No. M60252
    A potent, selective and cell permeable lysine methyltransferase SETD8 inhibitor.
  20. SGC0946, DOT1L inhibitor

    $139.00
    Catalog No. M60101
    A highly potent and selective inhibitor of DOT1L methyltransferase.
  21. SGC707, Allosteric PRMT3 Inhibitor

    $129.00
    Catalog No. M60243
    A potent, selective and cell permeable allosteric protein arginine methyltransferase 3 (PRMT3) inhibitor.
  22. UNC0379, Lysine Methyltransferase SETD8 Inhibitor

    $129.00
    Catalog No. M60207
    A novel selective, substrate-competitive inhibitor of the lysine methyltransferase SETD8
  23. UNC0638, G9a HMTase Inhibitor

    $89.00
    Catalog No. M66056
    A potent, selective and cell permeable inhibitor of G9a (EHMT2) and GLP (EHMT1) histone methyltransferases.
  24. UNC0642, G9a/GLP HMTase Inhibitor

    $129.00
    Catalog No. M60185
    A novel highly potent, selective and cell permeable inhibitor of the homologous protein lysine methyltransferases, G9a and GLP, with improved PK properties.
  25. UNC0646, G9a/GLP HMTase Inhibitor

    $89.00
    Catalog No. M60184
    A novel potent, selective and cell permeable homologous protein lysine methyltransferases G9a and GLP inhibitor.
  26. UNC2327, Allosteric PRMT3 Inhibitor

    $129.00
    Catalog No. M60253
    A potent and selective allosteric protein arginine methyltransferase 3 (PRMT3) inhibitor.
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