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Histone Methyltransferase

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  1. EPZ-5676 --- DOT1L inhibitor

    $139.00
    Catalog No. M60123
    A highly potent and selective inhibitor of DOT1L methyltransferase with Ki of 70 pM, selectively blocking the binding of the cofactor, S-adenosylmethionine.
  2. PFI-2, SETD7 Histone Lysine Methyltransferase Inhibitor

    $139.00
    Catalog No. M60182
    PFI-2 is a novel potent and selective SETD7 histone lysine methyltransferase inhibitor.
  3. SGC0946, DOT1L inhibitor

    $139.00
    Catalog No. M60101
    A highly potent and selective inhibitor of DOT1L methyltransferase.
  4. A-366, G9a/GLP HMTase Inhibitor

    $139.00
    Catalog No. M60210
    A novel highly potent, selective and cell permeable G9a/GLP histone lysine methyltransferase inhibitor.
  5. DZNep (3-Deazaneplanocin A) --- Histone Methyltransferase Inhibitor

    $129.00
    Catalog No. M60141
    An S-adenosylhomocysteine hydrolase inhibitor, indirectly inhibiting histone methyltransferases and decreasing global DNA methylation
  6. EPZ-6438, EZH2 Methyltransferase Inhibitor

    $129.00
    Catalog No. M60122
    EPZ-6438 (E7438) is a potent and selective small molecule inhibitor of histone methyltransferase EZH2 in clinical development.
  7. GSK126, EZH2 Methyltransferase Inhibitor.

    $129.00
    Catalog No. M60071
    GSK126 is a highly potent and selective small molecule inhibitor of histone methyltransferase EZH2.
  8. CPI-169, EZH2 Methyltransferase Inhibitor

    $129.00
    Catalog No. M60275
    A highly potent and selective small molecule inhibitor of histone methyltransferase EZH2.
  9. UNC0642, G9a/GLP HMTase Inhibitor

    $129.00
    Catalog No. M60185
    A novel highly potent, selective and cell permeable inhibitor of the homologous protein lysine methyltransferases, G9a and GLP, with improved PK properties.
  10. UNC0379, Lysine Methyltransferase SETD8 Inhibitor

    $129.00
    Catalog No. M60207
    A novel selective, substrate-competitive inhibitor of the lysine methyltransferase SETD8
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