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Immune modulator

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Items 1 to 17 of 17 total

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  1. (+)-JQ1, BET Inhibitor

    $109.00   $139.00
    Catalog No. M60139
    A potent and selective inhibitor of the bromodomain and extra terminal (BET) family proteins BRD2, BRD3, and BRD4
  2. AMI-1, Histone Methyltransferase Inhibitor

    $79.00
    Catalog No. M60272
    A potent and specific small molecule inhibitor of histone methyltransferase targeting yeast Hmt1p and human PRMT1.
  3. BAF312, S1P1/5 Selective Agonist

    $129.00
    Catalog No. M60039
    A potent and selective sphingosine 1-phosphate (S1P1/5) receptor agonist in clinical trials.
  4. Carfilzomib, Proteasome Inhibitor

    $109.00
    Catalog No. M60109
    A selective, irreversible proteasome inhibitor.
  5. CPI203, BET Inhibitor

    $139.00
    Catalog No. M60124
    A novel potent, selective and cell permeable inhibitor of the bromodomain and extra terminal (BET) family protein BRD4, inhibiting Myc expression.
  6. DMXAA (Vadimezan), mSTING Agonist

    $79.00
    Catalog No. M60301
    A potent and selective mSTING agonist, selective for mouse STING over human STING.
  7. GS143, IkappaB Ubiquitination Inhibitor

    $129.00
    Catalog No. M60308
    A selective β-TrCP1 ligase inhibitor
  8. GSK-J1, H3K27 Histone Demethylases UTX and JMJD3 Inhibitor

    $109.00
    Catalog No. M60062
    The first selective and potent inhibitor of the H3K27 histone demethylases UTX and JMJD3.
  9. GSK-J4, H3K27 Histone Demethylases UTX and JMJD3 Inhibitor

    $109.00
    Catalog No. M60063
    An ethyl ester derivative of GSK-J1 as a pro-drug for cellular assays; the first selective and potent inhibitor of the H3K27 histone demethylases UTX and JMJD3.
  10. Hydroxychloroquine (HCQ), Autophagy and TLR9 Inhibitor

    $49.00
    Catalog No. M60302
    A potent autophagy inhibitor and TLR9 inhibitor
  11. I-BET762 (GSK525762), BET Inhibitor

    $139.00
    Catalog No. M60154
    A novel, highly potent, selective and cell permeable BET inhibitor in clinical trials.
  12. INCB024360 (Epacadostat), IDO Inhibitor

    $109.00
    Catalog No. M60292
    A potent and selective indoleamine 2,3-dioxygenase (IDO1) inhibitor.
  13. MEK162 (ARRY-162), MEK Inhibitor

    $119.00
    Catalog No. M60080
    A highly potent, selective, and orally bioavailable MEK inhibitor in clinical trials.
  14. NLG919 (RG6078), IDO Inhibitor

    $129.00
    Catalog No. M60258
    A potent, selective and orally bioavailable IDO (indoleamine-(2,3)-dioxygenase) pathway inhibitor.
  15. PFI-1, BET Inhibitor

    $129.00
    Catalog No. M60120
    PFI-1 is a novel potent, selective and cell permeable inhibitor of the bromodomain and extra terminal (BET) family proteins BRD2 and BRD4.
  16. TMP269, Class IIa HDAC Inhibitor

    $129.00
    Catalog No. M60119
    A highly potent, selective and cell-permeable class IIa HDAC inhibitor.
  17. Y-320---IL-17 Immunomodulator

    $89.00
    Catalog No. M60200
    An orally active potent immunomodulator, inhibits IL-15-induced IL-17 production by CD4 T cells.
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