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Kinase

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  1. A83-01, TGF-β Inhibitor

    $59.00
    Catalog No. M60021
    A potent and selective TGF-β pathway inhibitor (targeting ALK4, ALK5 and ALK7).
  2. AA92593, Antagonist of Melanopsin-mediated Photo-transduction

    $139.00
    Catalog No. M60143
    A potent and selective small molecule antagonist of melanopsin-mediated photo-transduction.
  3. AZD6244 (Selumetinib), MEK Inhibitor

    $109.00
    Catalog No. M60067
    A potent and highly selective non-ATP competitive MEK inhibitor in clinical trials.
  4. BI-2536, PLK1 and BRD4 Dual Inhibitor

    $119.00
    Catalog No. M60171
    BI-2536 is a potent inhibitor of PLK1 (Polo-like kinase 1) and BRD4 in clinical trials.
  5. BIBW2992(Afatinib), EGFR Inhibitor

    $109.00
    Catalog No. M60065-5s
    A potent and selective irreversible inhibitor of EGFR/HER2 in clinical trials.
  6. CP-690550, JAK Inhibitor

    $79.00
    Catalog No. M60033
    A potent and selective pan-JAK Inhibitor in clinical trials for rheumatoid arthritis.
  7. CUDC-101, HDAC/EGFR/HER2 Inhibitor

    $69.00
    Catalog No. M60092
    A potent multi-target inhibitor targeting HDAC, EGFR and HER2 in clinical trial.
  8. CX-4945, CK2 (Casein Kinase 2) Inhibitor

    $129.00
    Catalog No. M60267
    A potent, selective and bioavailable CK2 (Casein Kinase 2) Inhibitor.
  9. DASA-58 (ML203), Pyruvate Kinase M2 (PKM2) Activator

    $109.00
    Catalog No. M60305
    A potent and selective Pyruvate kinase M2 (PKM2) activator.
  10. GDC-0349, mTOR Inhibitor

    $129.00
    Catalog No. M60110
    A potent and selective ATP-competitive inhibitor of mTOR in clinical trials.
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