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Kinase

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  1. GDC-0449 (Vismodegib), Hedgehog Antagonist

    $79.00
    Catalog No. M60034
    A potent and specific hedgehog pathway inhibitor approved by FDA
  2. GDC-0941, PI3K Inhibitor

    $79.00
    Catalog No. M60111
    A highly potent, selective and orally bioavailable class-I PI3K kinase inhibitor.
  3. GNF4877, β Cell Proliferation Inducer

    $159.00
    Catalog No. M60294
    A highly potent and selective small molecule that promotes pancreatic β cell proliferation in rodent and human primary islets.
  4. GNF7156, β Cell Proliferation Inducer

    $139.00
    Catalog No. M60293
    A highly potent and selective small molecule that promotes pancreatic β cell proliferation in rodent and human primary islets.
  5. Go6893, PKC Inhibitor

    $129.00
    Catalog No. M60273
    A potent pan-PKC inhibitor.
  6. Harmine, DYRK1A Inhibitor

    $29.00
    Catalog No. M60241
    A potent, selective and orally bioavailable DYRK1A inhibitor.
  7. HG-10-102-01, LRRK2 Inhibitor

    $139.00
    Catalog No. M60061
    A brain penetrant potent and selective inhibitor of wild-type LRRK2 and the G2019S mutant.
  8. ID-8, DYRK Inhibitor

    $89.00
    Catalog No. M60102
    A potent and selective small molecule inhibitor of dual-specificity tyrosine phosphorylation- regulated kinase (DYRK).
  9. INDY, DYRK1A/B Inhibitor

    $79.00
    Catalog No. M60242
    A potent and selective DYRK1A/B inhibitor.
  10. IRE-3, IRE1a Modulator

    $129.00
    Catalog No. M60167
    A highly potent and selective small molecule modulator of IRE1α.
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