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Neurogenic

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  1. BMS-708163 (Avagacestat), γ-Secretase Inhibitor

    $89.00
    Catalog No. M60032
    A potent γ-secretase Inhibitor, more selective for APP than Notch, in clinical trials for Alzheimer's disease.
  2. C646, p300/CBP inhibitor

    $129.00
    Catalog No. M60129
    A potent, selective and cell-permeable p300/CBP histone acetyltransferase (HAT) inhibitor.
  3. CTEP, mGlu5 Antagonist

    $259.00
    Catalog No. M60099
    A highly potent, selective and orally bioavailable allosteric antagonist of mGlu5 receptor.
  4. DAPT, γ-secretase Inhibitor

    $300.00
    Catalog No. M60023
    A γ-secretase inhibitor and widely used as a Notch pathway inhibitor.
  5. HG-10-102-01, LRRK2 Inhibitor

    $139.00
    Catalog No. M60061
    A brain penetrant potent and selective inhibitor of wild-type LRRK2 and the G2019S mutant.
  6. ISRIB (trans-isomer), Inhibitor of “Integrated Stress Response” (ISR)

    $129.00
    Catalog No. M60125
    A potent and selective small molecule inhibitor of PERK signaling that can potently reverse the effects of eIF2α phosphorylation, Inhibitor of “Integrated Stress Response” (ISR).
  7. ISX9, Neurogenic Modulator

    $99.00
    Catalog No. M60274
    A neurogenic modulator.
  8. J147, Neuroprotective Small Molecule

    $89.00
    Catalog No. M60012
    A potent and orally active neurotrophic molecule with broadly neuroprotective efficacy in vitro and in vivo.
  9. KL001, Cryptochrome Activator

    $79.00
    Catalog No. M66044
    A novel small molecule specifically interacting with cryptochrome (CRY) and causing lengthening of the circadian period.
  10. LY411575, γ-secretase Inhibitor

    $119.00
    Catalog No. M60078
    A highly potent, selective, and orally bioavailable inhibitor of gamma secretase.
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