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  1. DAPT, γ-secretase Inhibitor

    Catalog No. M60023
    A γ-secretase inhibitor and widely used as a Notch pathway inhibitor.
  2. CTEP, mGlu5 Antagonist

    Catalog No. M60099
    A highly potent, selective and orally bioavailable allosteric antagonist of mGlu5 receptor.
  3. HG-10-102-01, LRRK2 Inhibitor

    Catalog No. M60061
    A brain penetrant potent and selective inhibitor of wild-type LRRK2 and the G2019S mutant.
  4. SGC-CBP30, p300/CBP Bromodomain Inhibitor

    Catalog No. M60138
    SGC-CBP30 is a highly potent and selective p300/CBP bromodomain inhibitor
  5. C646, p300/CBP inhibitor

    Catalog No. M60129
    A potent, selective and cell-permeable p300/CBP histone acetyltransferase (HAT) inhibitor.
  6. Optovin, TRPA1 Activator

    Catalog No. M60103
    A potent and selective small molecule activator of human TRPA1.
  7. ISRIB (trans-isomer), Inhibitor of “Integrated Stress Response” (ISR)

    Catalog No. M60125
    A potent and selective small molecule inhibitor of PERK signaling that can potently reverse the effects of eIF2α phosphorylation, Inhibitor of “Integrated Stress Response” (ISR).
  8. NAB2, Rsp5/Nedd4 pathway activator, rescuing α-synuclein toxicity

    Catalog No. M60153
    A novel and highly potent small molecule Rsp5/Nedd4 pathway activator that was shown to strongly and selectively protect diverse cell types from α-synuclein toxicity.
  9. SAG, Hedgehog Agonist

    Catalog No. M60081
    A potent, selective, and cell-permeable small-molecule agonist of the Hedgehog pathway.
  10. TMP269, Class IIa HDAC Inhibitor

    Catalog No. M60119
    A highly potent, selective and cell-permeable class IIa HDAC inhibitor.
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