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Small Molecules

For our customers’ convenience, we provide ready-to-use sterile compound solution at 10 mM stock concentration dissolved in anhydrous pure and biological-grade DMSO. Our QC lab independently tests every batch of compounds to make sure their high purity by LC/MS and NMR. The DMSO stock solutions are further tested in cell culture to ensure there is no undesired activity. Our partner labs have also functionally tested our new compounds to ensure their activity before we offer them for the first time to the research community.
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  1. FH1, Hepatocytes Functional Enhancer

    Catalog No. M60127
    FH1 is a potent and selective small molecule that enhances hepatocyte functions and promotes the differentiation and maturation of iPSC-derived hepatocytes toward a more mature phenotype in vitro.
  2. FLI-06, Notch Pathway Modulator

    Catalog No. M60149
    FLI-06 is a novel potent and selective small molecule intercepting Notch signaling and the early secretory pathway (EC50 ~2.3 µM), identified by using automated microscopy to monitor the trafficking and processing of a ligand-independent Notch-GFP fusion reporter.
  3. Forskolin, Adenylyl Cyclase Activator

    Catalog No. M60024
    A potent adenylate cyclase activator to increase the intracellular levels of cAMP.
  4. FPH1, Hepatocytes Functional Proliferation Inducer

    Catalog No. M60126
    FPH1 is a potent and selective small molecule that induced Functional Proliferation of primary human Hepatocytes in vitro, identified by a high-throughput, cell-based screening using primary human hepatocytes.
  5. Furamidine, PRMT1 Inhibitor

    Catalog No. M60256
    A potent, selective and cell permeable Protein arginine methyltransferase-1 (PRMT1) inhibitor.
  6. GDC-0068, Akt Inhibitor

    Catalog No. M60066
    A novel potent and selective ATP competitive Akt inhibitor in clinical trials.
  7. GDC-0349, mTOR Inhibitor

    Catalog No. M60110
    A potent and selective ATP-competitive inhibitor of mTOR in clinical trials.
  8. GDC-0449 (Vismodegib), Hedgehog Antagonist

    Catalog No. M60034
    A potent and specific hedgehog pathway inhibitor approved by FDA
  9. GDC-0941, PI3K Inhibitor

    Catalog No. M60111
    A highly potent, selective and orally bioavailable class-I PI3K kinase inhibitor.
  10. GN44028, HIF-1α Inhibitor

    Catalog No. M60325
    A potent and selective HIF-1α inhibitor.
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