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Small Molecules

For our customers’ convenience, we provide ready-to-use sterile compound solution at 10 mM stock concentration dissolved in anhydrous pure and biological-grade DMSO. Our QC lab independently tests every batch of compounds to make sure their high purity by LC/MS and NMR. The DMSO stock solutions are further tested in cell culture to ensure there is no undesired activity. Our partner labs have also functionally tested our new compounds to ensure their activity before we offer them for the first time to the research community.
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Items 81 to 90 of 318 total

  1. EML425, CBP/p300 Inhibitor

    Catalog No. M60257
    A selective, noncompetitive and cell permeable KAT3 histone acetyltransferases CBP/p300 inhibitor.
  2. Entinostat (MS-275) -- HDAC Inhibitor

    Catalog No. M60174
    Entinostat (MS-275) is a potent and selective HDAC1 and HDAC3 inhibitor.
  3. EPZ-5676 --- DOT1L inhibitor

    Catalog No. M60123
    A highly potent and selective inhibitor of DOT1L methyltransferase with Ki of 70 pM, selectively blocking the binding of the cofactor, S-adenosylmethionine.
  4. EPZ-6438, EZH2 Methyltransferase Inhibitor

    Catalog No. M60122
    EPZ-6438 (E7438) is a potent and selective small molecule inhibitor of histone methyltransferase EZH2 in clinical development.
  5. EPZ015666 (GSK3235025), PRMT5 Inhibitor

    Catalog No. M60254
    A potent, selective and orally bioavailable Protein arginine methyltransferase-5 (PRMT5) Inhibitor.
  6. EX-527, SIRT1 Inhibitor

    Catalog No. M60108
    EX-527 is a highly potent and selective inhibitor of SIRT1 with an IC50 ~98 nM.
  7. FASCIN-G2, Fascin Inhibitor

    Catalog No. M60269
    A potent, selective and bioavailable small molecule that inhibits the actin-bundling activity of fascin.
  8. Fatostatin A, Sterol Regulatory Binding Proteins (SREBPs) Inhibitor

    Catalog No. M60180
    Fatostatin A is a highly potent, specific and cell permeable inhibitor of Sterol Regulatory Binding Proteins (SREBPs).
  9. Ferrostatin-1 (Fer-1), Ferroptosis Inhibitor

    Catalog No. M60042
    Ferrostatin-1 (Fer-1) is a potent inhibitor of ferroptosis with an EC50 ~60 nM, identified by a HTS using erastin-induced ferroptosis in HT-1080 cells.
  10. FG-4592 (Roxadustat), HIF Prolyl-Hydroxylases Inhibitor

    Catalog No. M60263
    A potent, selective and bioavailable inhibitor of hypoxia-inducible factor prolyl hydroxylase.
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Items 81 to 90 of 318 total