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Small Molecules


For our customers’ convenience, we provide ready-to-use sterile compound solution at 10 mM stock concentration dissolved in anhydrous pure and biological-grade DMSO. Our QC lab independently tests every batch of compounds to make sure their high purity by LC/MS and NMR. The DMSO stock solutions are further tested in cell culture to ensure there is no undesired activity. Our partner labs have also functionally tested our new compounds to ensure their activity before we offer them for the first time to the research community.
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  1. Nocodazole, Microtubule Inhibitor / CRISPR Editing Enhancer

    $79.00
    Catalog No. M60331
    A potent microtubule inhibitor to inhibit mitosis and CRISPR editing enhancer.
  2. (+)-JQ1, BET Inhibitor

    $109.00   $139.00
    Catalog No. M60139
    A potent and selective inhibitor of the bromodomain and extra terminal (BET) family proteins BRD2, BRD3, and BRD4
  3. (R)-2-HG, a-KG-dependent dioxygenases inhibitor

    $69.00
    Catalog No. M60104
    An a-KG-dependent dioxygenases inhibitor
  4. (S)-crizotinib, MTH1 Inhibitor

    $99.00
    Catalog No. M60208
    A novel potent, selective and cell permeable MTH1 inhibitor.
  5. (Z)-4-Hydroxytamoxifen, CRISPR Editing Enhancer

    $89.00
    Catalog No. M60324
    Previously characterized as an Estrogen Receptor antagonist and now found to improve genome-editing specificity in CRISPR-mediated gene editing
  6. 1,4-DPCA, Prolyl 4-hydroxylase (P4H) Inhibitor

    $29.00
    Catalog No. M60288
    A selective and cell permeable prolyl 4-hydroxylase (P4H) inhibitor.
  7. 1-methyl-D-tryptophan (D-1MT), IDO Inhibitor

    $29.00
    Catalog No. M60291
    A potent and selective indoleamine 2,3-dioxygenase (IDO) inhibitor.
  8. 4SC-202, HDAC/LSD1 Dual Inhibitor

    $109.00
    Catalog No. M60230
    A potent, selective and orally bioavailable HDAC/LSD1 dual Inhibitor.
  9. 5-Azacytidine, DNA Methyltransferase Inhibitor

    $59.00
    Catalog No. M60131
    A classic DNA methyltransferase inhibitor, incorporates into DNA forming covalent adducts with cellular DNMT, depleting enzyme activity.
  10. A-366, G9a/GLP HMTase Inhibitor

    $139.00
    Catalog No. M60210
    A novel highly potent, selective and cell permeable G9a/GLP histone lysine methyltransferase inhibitor.
  11. A01, Smurf1 E3 Ubiquitin Ligase Inhibitor

    $109.00
    Catalog No. M60249
    A potent and selective Smurf1 E3 ubiquitin ligase inhibitor.
  12. A769662, AMPK Activator

    $79.00
    Catalog No. M60020
    A potent allosteric AMPK activator.
  13. A83-01, TGF-β Inhibitor

    $59.00
    Catalog No. M60021
    A potent and selective TGF-β pathway inhibitor (targeting ALK4, ALK5 and ALK7).
  14. AA92593, Antagonist of Melanopsin-mediated Photo-transduction

    $139.00
    Catalog No. M60143
    A potent and selective small molecule antagonist of melanopsin-mediated photo-transduction.
  15. Abiraterone, CYP17 inhibitor Abiraterone (CB-7598)

    $69.00
    Catalog No. M60031
    A first-in-class CYP17 inhibitor approved to treat castration-resistant prostate cancer.
  16. ABT-199, BCL-2 inhibitor

    $99.00
    Catalog No. M60075
    A potent BCL-2–selective (BCL-X L) inhibitor with clinical efficacy.
  17. ACY-1215 (Rocilinostat), HDAC6 inhibitor

    $109.00
    Catalog No. M60076
    A highly potent, selective, and orally bioavailable inhibitor of histone deacetylase 6 (HDAC6).
  18. AdipoRon, Adiponectin Receptor/AdipoR agonist

    $129.00
    Catalog No. M60152
    A novel, highly potent, selective and orally active small molecule agonist of adiponectin receptor (AdipoR).
  19. AG-120 (Ivosidenib), IDH1 Inhibitor

    $129.00
    Catalog No. M60318
    A potent, selective and reversible inhibitor of IDH1 in clinical trials.
  20. AG-221 (Enasidenib), IHD2 Inhibitor

    $129.00
    Catalog No. M60296
    A potent and selective inhibitor of IDH2 R140Q mutant.
  21. AGI-5198 (IDH-C35), Mutant IDH1 Inhibitor

    $109.00
    Catalog No. M60068
    The first highly potent and selective mutant IDH1 inhibitor that was shown to have anti-tumor efficacy in vivo.
  22. AGI-6780, Mutant IDH2 Inhibitor

    $109.00
    Catalog No. M60105
    The first highly potent and selective small molecule mutant IDH2 inhibitor.
  23. AK-7, SIRT2 Inhibitor

    $69.00
    Catalog No. M60107
    A cell- and brain-permeable, selective sirtuin SIRT2 inhibitor, displays no effect on SIRT1 or SIRT3.
  24. AMI-1, Histone Methyltransferase Inhibitor

    $79.00
    Catalog No. M60272
    A potent and specific small molecule inhibitor of histone methyltransferase targeting yeast Hmt1p and human PRMT1.
  25. APY29, IRE1a Modulator

    $109.00
    Catalog No. M60168
    A highly potent and selective small molecule modulator of IRE1α.
  26. AR7, RARα antagonist

    $129.00
    Catalog No. M60116
    A highly potent and selective enhancer of the chaperone-mediated autophagy (CMA) through antagonizing RARα.
  27. AS2034178, GPR40 Agonist

    $139.00
    Catalog No. M60221
    A potent, selective and orally bioavailable GPR40 (FFA1) agonist.
  28. AS8351, KDM5B Inhibitor

    $109.00
    Catalog No. M60330
    A potent iron chelator that has been found to inhibit of histone demethylase KDM5B (JARID1B).
  29. Atglistatin, Adipose Triglyceride Lipase (ATGL) Inhibitor

    $119.00
    Catalog No. M60150
    A highly potent, selective and competitive inhibitor of adipose triglyceride lipase (ATGL).
  30. AZD2014, mTOR Inhibitor

    $169.00
    Catalog No. M60090
    A highly potent, selective and ATP-competitive mTOR inhibitor with a high level of selectivity against other members of the PIKK family.
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