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Small Molecules

For our customers’ convenience, we provide ready-to-use sterile compound solution at 10 mM stock concentration dissolved in anhydrous pure and biological-grade DMSO. Our QC lab independently tests every batch of compounds to make sure their high purity by LC/MS and NMR. The DMSO stock solutions are further tested in cell culture to ensure there is no undesired activity. Our partner labs have also functionally tested our new compounds to ensure their activity before we offer them for the first time to the research community.
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  1. UNC0638, G9a HMTase Inhibitor

    Catalog No. M66056
    A potent, selective and cell permeable inhibitor of G9a (EHMT2) and GLP (EHMT1) histone methyltransferases.
  2. Purmorphamine, Hedgehog Agonist

    Catalog No. M66055
    A selective hedgehog pathway agonist (Smo agonist).
  3. IOX2, HIF Prolyl-Hydroxylases (PHD2) Inhibitor

    Catalog No. M66054
    A potent and selective PHD (HIF prolyl-hydroxylases) inhibitor with cellular activity.
  4. I-BET151 (GSK1210151A), BET Inhibitor

    Catalog No. M66053
    A potent and selective inhibitor of the bromodomain and extra terminal (BET) family proteins BRD2, BRD3, and BRD4.
  5. CX-5461, RNA Polymerase I inhibitor

    Catalog No. M66052
    A potent and selective RNA Polymerase I inhibitor, for anti-tumor use.
  6. NVP-BKM120, PI3K Inhibitor BKM120

    Catalog No. M66051
    A selective PI3K Inhibitor in clinical trials for advanced solid tumors.
  7. NVP-BGT226, PI3K/mTOR Dual Inhibitor

    Catalog No. M66050
    A PI3K/mTOR dual inhibitor in clinical trials for advanced solid tumors.
  8. SR9011, REV-ERB Agonist

    Catalog No. M66049
    A potent synthetic REV-ERB agonist with in vivo activity; can regulate circadian behavior and metabolism.
  9. SR1664,PPAR-γ Modulator

    Catalog No. M66048
    An unique PPARγ modulator that has potent anti-diabetic activity through blocking the Cdk5-mediated phosphorylation of PPARγ, but completely lacks classical transcriptional agonism that accounts for other PPARγ agonists’ side effects.
  10. NSC319726, Mutant p53 Activator

    Catalog No. M66047
    A potent and selective activator of the most common p53R175 mutant, restoring the mutant p53 to its WT structure and function.
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