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Small Molecules

For our customers’ convenience, we provide ready-to-use sterile compound solution at 10 mM stock concentration dissolved in anhydrous pure and biological-grade DMSO. Our QC lab independently tests every batch of compounds to make sure their high purity by LC/MS and NMR. The DMSO stock solutions are further tested in cell culture to ensure there is no undesired activity. Our partner labs have also functionally tested our new compounds to ensure their activity before we offer them for the first time to the research community.
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  1. CRISPR Editing Tool Box

    Catalog No. LI30010
    Compound collection for CRISPR editing.
  2. CHIR99021, GSK3β Inhibitor

    Catalog No. M60002
    The most widely used, potent and selective GSK3β Inhibitor; Wnt pathway activator.
  3. DAPT, γ-secretase Inhibitor

    Catalog No. M60023
    A γ-secretase inhibitor and widely used as a Notch pathway inhibitor.
  4. SB431542, TGF-beta Inhibitor

    Catalog No. M60015
    A potent and selective TGF-β pathway inhibitor (selective for ALK4, ALK5 and ALK7).
  5. CTEP, mGlu5 Antagonist

    Catalog No. M60099
    A highly potent, selective and orally bioavailable allosteric antagonist of mGlu5 receptor.
  6. TH-302, Hypoxia-activated Pro-drug

    Catalog No. M60089
    A highly potent and selective hypoxia-activated pro-drug targeting hypoxic regions of solid tumors.
  7. AZD2014, mTOR Inhibitor

    Catalog No. M60090
    A highly potent, selective and ATP-competitive mTOR inhibitor with a high level of selectivity against other members of the PIKK family.
  8. LY2157299, TGFβ Inhibitor

    Catalog No. M60064
    A novel potent and selective TGFβ receptor type I and type II (TβRI/II) inhibitor with IC50 of 86 nM and 2 nM respectively.
  9. UM171, Human HSC Self-renewal Agonist

    Catalog No. M60223
    A potent small molecules that stimulates the expansion ex vivo of human cord blood cells capable of reconstituting human hematopoiesis for at least 6 months in immunocompromised mice.
  10. GDC-0068, Akt Inhibitor

    Catalog No. M60066
    A novel potent and selective ATP competitive Akt inhibitor in clinical trials.
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