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Wnt pathway

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Items 1 to 10 of 11 total

  1. CHIR99021, GSK3β Inhibitor

    $390.00
    Catalog No. M60002
    The most widely used, potent and selective GSK3β Inhibitor; Wnt pathway activator.
  2. HLY78, Wnt Activator

    $149.00
    Catalog No. M60140
    An activator of the Wnt pathway by targeting the DIX domain of Axin and potentiating the Axin–LRP6 association, thus promoting LRP6 phosphorylation and Wnt signaling transduction.
  3. ID-8, DYRK Inhibitor

    $89.00
    Catalog No. M60102
    A potent and selective small molecule inhibitor of dual-specificity tyrosine phosphorylation- regulated kinase (DYRK).
  4. IWP-2, Porcupine (Wnt) Inhibitor

    $79.00
    Catalog No. M60115
    A potent and highly selective Wnt signaling antagonist targeting porcupine.
  5. KY02111, Wnt Inhibitor

    $109.00
    Catalog No. M60073
    A potent and selective Wnt inhibitor promotes differentiation of hESCs/iPSCs to cardiomyocytes; might function downstream from GSK3β and APC in b-catenin destruction complex
  6. KYA1797K, Wnt/β-catenin Inhibitor

    $129.00
    Catalog No. M60317
    A highly potent and selective Wnt/β-catenin inhibitor binding directly to the regulators of G-protein signaling domain of axin.
  7. LGK974, Porcupine (Wnt) Inhibitor

    $139.00
    Catalog No. M60106
    A highly potent, selective and orally bioavailable Porcupine inhibitor (Wnt signaling antagonist) in clinical trials.
  8. MSAB, β-catenin Inhibitor

    $129.00
    Catalog No. M60316
    A potent and selective Wnt/β-catenin inhibitor identified using cell-based chemical screening.
  9. WAY-316606, Secreted Frizzled-related Protein-1 (sFRP-1) Inhibitor

    $139.00
    Catalog No. M60215
    A novel potent and selective inhibitor of secreted frizzled-related protein-1 (sFRP-1) to increase Wnt signaling.
  10. Wnt-C59, Wnt Antagonist

    $89.00
    Catalog No. M60005
    A potent, selective and oral active Wnt  signaling pathway antagonist.
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