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Wnt pathway

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Items 1 to 10 of 12 total

  1. XAV939---Wnt Antagonist

    Catalog No. M60010
    A potent and selective Wnt pathway antagonist; functions to stabilize axin by inhibiting tankyrase 1 and tankyrase 2.
  2. Wnt-C59, Wnt Antagonist

    Catalog No. M60005
    A potent, selective and oral active Wnt  signaling pathway antagonist.
  3. WAY-316606, Secreted Frizzled-related Protein-1 (sFRP-1) Inhibitor

    Catalog No. M60215
    A novel potent and selective inhibitor of secreted frizzled-related protein-1 (sFRP-1) to increase Wnt signaling.
  4. NVP-TNKS656, Wnt / Tankyrase Inhibitor

    Catalog No. M60328
    A highly potent, selective and oral bioavailable tankyrase inhibitor for TNKS2.
  5. MSAB, β-catenin Inhibitor

    Catalog No. M60316
    A potent and selective Wnt/β-catenin inhibitor identified using cell-based chemical screening.
  6. LGK974, Porcupine (Wnt) Inhibitor

    Catalog No. M60106
    A highly potent, selective and orally bioavailable Porcupine inhibitor (Wnt signaling antagonist) in clinical trials.
  7. KYA1797K, Wnt/β-catenin Inhibitor

    Catalog No. M60317
    A highly potent and selective Wnt/β-catenin inhibitor binding directly to the regulators of G-protein signaling domain of axin.
  8. KY02111, Wnt Inhibitor

    Catalog No. M60073
    A potent and selective Wnt inhibitor promotes differentiation of hESCs/iPSCs to cardiomyocytes; might function downstream from GSK3β and APC in b-catenin destruction complex
  9. IWP-2, Porcupine (Wnt) Inhibitor

    Catalog No. M60115
    A potent and highly selective Wnt signaling antagonist targeting porcupine.
  10. ID-8, DYRK Inhibitor

    Catalog No. M60102
    A potent and selective small molecule inhibitor of dual-specificity tyrosine phosphorylation- regulated kinase (DYRK).
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