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  1. (S)-crizotinib, MTH1 Inhibitor

    $99.00
    Catalog No. M60208
    A novel potent, selective and cell permeable MTH1 inhibitor.
  2. 4SC-202, HDAC/LSD1 Dual Inhibitor

    $109.00
    Catalog No. M60230
    A potent, selective and orally bioavailable HDAC/LSD1 dual Inhibitor.
  3. A-366, G9a/GLP HMTase Inhibitor

    $139.00
    Catalog No. M60210
    A novel highly potent, selective and cell permeable G9a/GLP histone lysine methyltransferase inhibitor.
  4. A01, Smurf1 E3 Ubiquitin Ligase Inhibitor

    $109.00
    Catalog No. M60249
    A potent and selective Smurf1 E3 ubiquitin ligase inhibitor.
  5. AdipoRon, Adiponectin Receptor/AdipoR agonist

    $129.00
    Catalog No. M60152
    A novel, highly potent, selective and orally active small molecule agonist of adiponectin receptor (AdipoR).
  6. AG-120 (Ivosidenib), IDH1 Inhibitor

    $129.00
    Catalog No. M60318
    A potent, selective and reversible inhibitor of IDH1 in clinical trials.
  7. AG-221 (Enasidenib), IHD2 Inhibitor

    $129.00
    Catalog No. M60296
    A potent and selective inhibitor of IDH2 R140Q mutant.
  8. APY29, IRE1a Modulator

    $109.00
    Catalog No. M60168
    A highly potent and selective small molecule modulator of IRE1α.
  9. AR7, RARα antagonist

    $129.00
    Catalog No. M60116
    A highly potent and selective enhancer of the chaperone-mediated autophagy (CMA) through antagonizing RARα.
  10. AS2034178, GPR40 Agonist

    $139.00
    Catalog No. M60221
    A potent, selective and orally bioavailable GPR40 (FFA1) agonist.
  11. Atglistatin, Adipose Triglyceride Lipase (ATGL) Inhibitor

    $119.00
    Catalog No. M60150
    A highly potent, selective and competitive inhibitor of adipose triglyceride lipase (ATGL).
  12. b-AP15 (NSC687852), Deubiquitinases Inhibitor

    $89.00
    Catalog No. M60251
    A potent and selective deubiquitinases inhibitor for 19S proteasomes activity of Ub-AMC cleavage.
  13. BAM7, BAX Activator

    $109.00
    Catalog No. M60069
    The first potent and selective small molecule activator of BAX, which is a pro-apoptotic BCL-2 family member.
  14. BAY 87-2243, Hypoxia-inducible Factor-1 (HIF-1) Inhibitor

    $119.00
    Catalog No. M60217
    A highly potent and selective hypoxia-inducible factor-1 (HIF-1) inhibitor.
  15. BAZ2-ICR, BAZ2 Bromodomain Inhibitor

    $129.00
    Catalog No. M60226
    A potent and selective BAZ2 bromodomain inhibitor.
  16. BG45, HDAC3 Inhibitor

    $59.00
    Catalog No. M60266
    A potent, selective and cell permeable HDAC3 inhibitor.
  17. BI-7273, BRD9 Bromodomain Inhibitor

    $129.00
    Catalog No. M60322
    A potent, selective and cell-permeable BRD9 inhibitor.
  18. BI-9564, BRD9 Bromodomain Inhibitor

    $129.00
    Catalog No. M60323
    A potent, selective and cell-permeable BRD9 inhibitor.
  19. Bioymifi, TRAIL Receptor DR5 Activator

    $109.00
    Catalog No. M60088
    A potent and selective small molecule agonist of DR5.
  20. BQU57, GTPase Ral Inhibitor

    $139.00
    Catalog No. M60228
    A potent and selective GTPase Ral Inhibitor
  21. Bromosporine, Pan-bromodomain Inhibitor

    $129.00
    Catalog No. M60144
    A broad spectrum inhibitor for bromodomains.
  22. CAY10603, HDAC6 Inhibitor

    $129.00
    Catalog No. M60234
    A potent and selective HDAC6 inhibitor.
  23. CB-5083, p97 AAA ATPase Inhibitor

    $129.00
    Catalog No. M60306
    A highly potent, selective and orally bioavailable p97 AAA ATPase inhibitor.
  24. CPI-455, KDM5 Demethylases Inhibitor

    $129.00
    Catalog No. M60326
    A potent and selective KDM5A inhibitor.
  25. CPI203, BET Inhibitor

    $139.00
    Catalog No. M60124
    A novel potent, selective and cell permeable inhibitor of the bromodomain and extra terminal (BET) family protein BRD4, inhibiting Myc expression.
  26. CTEP, mGlu5 Antagonist

    $259.00
    Catalog No. M60099
    A highly potent, selective and orally bioavailable allosteric antagonist of mGlu5 receptor.
  27. Deltarasin, KRAS-PDEδ Inhibitor

    $139.00
    Catalog No. M60218
    A potent and selective small molecular inhibitor of KRAS-PDEδ interaction
  28. EED226, PRC2 Inhibitor

    $139.00
    Catalog No. M60327
    A potent and selective allosteric PRC2 inhibitor that directly binds to the H3K27me3 binding pocket of EED.
  29. EML425, CBP/p300 Inhibitor

    $129.00
    Catalog No. M60257
    A selective, noncompetitive and cell permeable KAT3 histone acetyltransferases CBP/p300 inhibitor.
  30. EPZ-5676 --- DOT1L inhibitor

    $139.00
    Catalog No. M60123
    A highly potent and selective inhibitor of DOT1L methyltransferase with Ki of 70 pM, selectively blocking the binding of the cofactor, S-adenosylmethionine.
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