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  1. CTEP, mGlu5 Antagonist

    $259.00
    Catalog No. M60099
    A highly potent, selective and orally bioavailable allosteric antagonist of mGlu5 receptor.
  2. THZ1, Covalent CDK7 Inhibitor

    $159.00
    Catalog No. M60214
    A novel potent, selective and cell permeable irreversible CDK7 inhibitor.
  3. GNF4877, β Cell Proliferation Inducer

    $159.00
    Catalog No. M60294
    A highly potent and selective small molecule that promotes pancreatic β cell proliferation in rodent and human primary islets.
  4. PF-04979064, PI3K/mTOR Dual Inhibitor

    $149.00
    Catalog No. M60114
    PF-04979064 is a highly potent and orally bioavailable PI3K/mTOR dual inhibitor developed through structure-based drug design.
  5. CPI203, BET Inhibitor

    $139.00
    Catalog No. M60124
    A novel potent, selective and cell permeable inhibitor of the bromodomain and extra terminal (BET) family protein BRD4, inhibiting Myc expression.
  6. EPZ-5676 --- DOT1L inhibitor

    $139.00
    Catalog No. M60123
    A highly potent and selective inhibitor of DOT1L methyltransferase with Ki of 70 pM, selectively blocking the binding of the cofactor, S-adenosylmethionine.
  7. ONX-0914, Immunoproteasome Inhibitor

    $139.00
    Catalog No. M60112
    A potent and selective immunoproteasome inhibitor.
  8. PFI-3, SMARCA Bromodomains Inhibitor

    $139.00
    Catalog No. M60175
    PFI-3 is a novel potent, selective and cell permeable inhibitor of SMARCA4 and PB1(5) bromodomains.
  9. I-CBP112, p300/CBP Bromodomain Inhibitor

    $139.00
    Catalog No. M60128
    A highly potent and selective p300/CBP bromodomain inhibitor.
  10. IDH-C227, IDH1 Inhibitor

    $139.00
    Catalog No. M60043
    A potent and selective inhibitor of the IDH1 R132H mutant with good cellular activity.
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