Nifenalol HCl

Nifenalol, also known as INPEA, is a new beta-adrenergic receptor antagonist.

Product information

CAS Number: 5704-60-9

Molecular Weight: 260.72

Formula: C11H17ClN2O3

Chemical Name: 2-(Isopropylamino)-1-(p-nitrophenyl)ethanol hydrochloride

Smiles: Cl.CC(C)NCC(O)C1=CC=C(C=C1)[N+]([O-])=O

InChiKey: STGOXRVTUNXXLQ-UHFFFAOYSA-N

InChi: InChI=1S/C11H16N2O3.ClH/c1-8(2)12-7-11(14)9-3-5-10(6-4-9)13(15)16;/h3-6,8,11-12,14H,7H2,1-2H3;1H

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: To be determined

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

1. Rabast U, Kasper H, Schönborn J, Knechtel B. [Blood glucose concentration and insulin activity in serum after administration of the beta receptor blockader nifenalol-HC1 (INPEA). Studies in metabolically healthy people and diabetics]. Ther Ggw. 1977 Jun;116(6):1162-74. German. PubMed PMID: 578017.
2. Nishimura T, Kita S, Abiko Y. Effects of 1-(4-nitrophenyl)-2-isopropylaminoethanol (INPEA) and propranolol and their dextro-isomers on hemodynamic and metabolic responses to isoproterenol in dogs. J Pharmacol Exp Ther. 1983 Aug;226(2):595-602. PubMed PMID: 6688273.
3. Hasslacher C, Wahl P, Riemer G. [Influence of the beta-receptor blocker nifenalol on insulin secretion in normal subjects and diabetic patients (author's transl)]. Arzneimittelforschung. 1977 Feb;27(2):426-9. German. PubMed PMID: 577165.

Products are for research use only. Not for human use.