Description
CK2/PIM1-IN-1 is an inhibitor of CK2 and PIM1, with IC50s of 3.787 μM and 4.327 μM for CK2 and PIM1, respectively. CK2/PIM1-IN-1 is developed for the research of proliferative disorders such as cancer, as well as other kinase-associated conditions including inflammation, pain, vascular disorders, pathogenic infections and certain immunological disorders.
Product information
CAS Number: 292640-28-9
Molecular Weight: 331.37
Formula: C15H9NO4S2
Chemical Name: 2-(5-{[(5E)-4-oxo-2-sulfanylidene-1, 3-thiazolidin-5-ylidene]methyl}furan-2-yl)benzoic acid
Smiles: OC(=O)C1=CC=CC=C1C1=CC=C(/C=C2/SC(=S)NC/2=O)O1
InChiKey: OTBNRWGTJUMXPA-KPKJPENVSA-N
InChi: InChI=1S/C15H9NO4S2/c17-13-12(22-15(21)16-13)7-8-5-6-11(20-8)9-3-1-2-4-10(9)14(18)19/h1-7H,(H,18,19)(H,16,17,21)/b12-7+
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: Soluble in DMSO
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
References:
- Mustapha Haddach, et al. Rhodanines and related heterocycles as kinase inhibitors. WO2010148351A1.
Products are for research use only. Not for human use.
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