Copper tripeptide

Copper tripeptide (GHK-Cu), a naturally occurring tripeptide, is first isolated from human plasma, but can be found in saliva and urine. During wound healing, Copper tripeptide may be freed from existing extracellular proteins via proteolysis and serves as a chemoattractant for inflammatory and endothelial cells. Copper tripeptide has been shown to increase messenger RNA production for collagen, elastin, proteoglycans, and glycosaminoglycans in fibroblasts. Copper tripeptide is a Natural Modulator of Multiple Cellular Pathways in Skin Regeneration.

Product information

CAS Number: 89030-95-5

Molecular Weight: 432.67

Formula: C28H42Cu3N12O8

Synonym:

GHK-Cu

Chemical Name: copper;(2S)-6-amino-2-[[(2S)-2-(2-azanidylacetyl)azanidyl-3-(1H-imidazol-4-yl)propanoyl]amino]hexanoate

Smiles: [Cu+2].[Cu+2].[Cu+2].[NH-]CC(=O)[N-][C@@H](CC1=CNC=N1)C(=O)N[C@@H](CCCCN)C([O-])=O.[NH-]CC(=O)[N-][C@@H](CC1=CNC=N1)C(=O)N[C@@H](CCCCN)C([O-])=O

InChiKey: KGIHFLSRHKZUCZ-PFVVTREHSA-J

InChi: InChI=1S/2C14H23N6O4.3Cu/c2*15-4-2-1-3-10(14(23)24)20-13(22)11(19-12(21)6-16)5-9-7-17-8-18-9;;;/h2*7-8,10-11,16H,1-6,15H2,(H4,17,18,19,20,21,22,23,24);;;/q2*-1;3*+2/p-4/t2*10-,11-;;;/m00.../s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: H2O : 62.5 mg/mL (155.90 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

1. Pollard JD, et al. Effects of copper tripeptide on the growth and expression of growth factors by normal and irradiated fibroblasts. Arch Facial Plast Surg. 2005 Jan-Feb;7(1):27-31.

Products are for research use only. Not for human use.