Anguizole

Anguizole is a potent NS4B-AH2 inhibitor. Anguizole disrupts all of NS4B-AH2-mediated biological functions of NS4B. hronic hepatitis C virus (HCV) infection is responsible for severe liver diseases including liver cirrhosis and hepatocellular carcinoma. An HCV non-structural protein 4B (NS4B) plays an essential role in viral RNA genome replication by building multi-vesicular structures around endoplasmic reticulum membranes.

Product information

CAS Number: 442666-98-0

Molecular Weight: 408.81

Formula: C17H11ClF2N4O2S

Chemical Name: 7-(chlorodifluoromethyl)-5-(furan-2-yl)-N-[(thiophen-2-yl)methyl]pyrazolo[1,5-a]pyrimidine-2-carboxamide

Smiles: O=C(NCC1=CC=CS1)C1C=C2N=C(C=C(N2N=1)C(F)(F)Cl)C1=CC=CO1

InChiKey: GBNREAYNZPJROB-UHFFFAOYSA-N

InChi: InChI=1S/C17H11ClF2N4O2S/c18-17(19,20)14-7-11(13-4-1-5-26-13)22-15-8-12(23-24(14)15)16(25)21-9-10-3-2-6-27-10/h1-8H,9H2,(H,21,25)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.