Description
Sacubitrilat (Sac, LBQ-657) is an active inhibitor of neprilysin (NEP).
Product information
CAS Number: 149709-44-4
Molecular Weight: 383.44
Formula: C22H25NO5
Synonym:
Sac
LBQ-657
Chemical Name: (2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-(3-carboxypropanamido)-2-methylpentanoic acid
Smiles: C[C@H](C[C@@H](CC1=CC=C(C=C1)C1=CC=CC=C1)NC(=O)CCC(O)=O)C(O)=O
InChiKey: DOBNVUFHFMVMDB-BEFAXECRSA-N
InChi: InChI=1S/C22H25NO5/c1-15(22(27)28)13-19(23-20(24)11-12-21(25)26)14-16-7-9-18(10-8-16)17-5-3-2-4-6-17/h2-10,15,19H,11-14H2,1H3,(H,23,24)(H,25,26)(H,27,28)/t15-,19+/m1/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO 77 mg/mL (200.81 mM) Ethanol 77 mg/mL (200.81 mM)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
References:
- Surya P Ayalasomayajula, et al. Eur J Clin Pharmacol. 2016 Sep
Products are for research use only. Not for human use.
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