MRS2698

MRS2698 is a potent and highly selective P2Y2 receptor agonist with an EC50 of 8 nM. MRS2698 is >300-fold P2Y2-selective versus the P2Y4 and P2Y6 receptors.

Product information

CAS Number: 934014-05-8

Molecular Weight: 483.22

Formula: C9H16N3O12P3S

Chemical Name: ({[({[(2S,3S,4R,5R)-4-amino-3-hydroxy-5-(4-oxo-2-sulfanylidene-1,2,3,4-tetrahydropyrimidin-1-yl)oxolan-2-yl]methyl}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphonic acid

Smiles: N[C@H]1[C@@H](O[C@H](CP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@H]1O)N1C=CC(=O)NC1=S

InChiKey: JFTKYXAPVLEOJM-XVFCMESISA-N

InChi: InChI=1S/C9H16N3O12P3S/c10-6-7(14)4(22-8(6)12-2-1-5(13)11-9(12)28)3-25(15,16)23-27(20,21)24-26(17,18)19/h1-2,4,6-8,14H,3,10H2,(H,15,16)(H,20,21)(H,11,13,28)(H2,17,18,19)/t4-,6-,7-,8-/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

MRS2698 is the 2′-amino-2-thio derivative of UTP and is one of the most potent and selective P2Y2R agonist. MRS2698 is 6-fold more potent than the endogenous agonist UTP.

Products are for research use only. Not for human use.