Description
MK-2894 is a potent and selective prostaglandin E2 subtype 4 receptor (PGE2) antagonist. MK-2894 exhibits favorable pharmacokinetic profile in a number of preclinical species and potent anti-inflammatory activity in several animal models of pain/inflammation. MK-2894 also shows favorable GI tolerability profile in rats when compared to traditional NSAID indomethacin.
Product information
CAS Number: 1006036-88-9
Molecular Weight: 495.49
Formula: C25H21F3NNaO3S
Chemical Name: sodium 4-[1-(2,5-dimethyl-4-{[4-(trifluoromethyl)phenyl]methyl}thiophene-3-amido)cyclopropyl]benzoate
Smiles: [Na+].CC1SC(C)=C(C=1CC1C=CC(=CC=1)C(F)(F)F)C(=O)NC1(CC1)C1C=CC(=CC=1)C([O-])=O
InChiKey: RQRUUNKVGDVBFV-UHFFFAOYSA-M
InChi: InChI=1S/C25H22F3NO3S.Na/c1-14-20(13-16-3-7-19(8-4-16)25(26,27)28)21(15(2)33-14)22(30)29-24(11-12-24)18-9-5-17(6-10-18)23(31)32;/h3-10H,11-13H2,1-2H3,(H,29,30)(H,31,32);/q;+1/p-1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥360 days if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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