Description
Boc-NH-C6-amido-C4-acid (PROTAC Linker 32) is an alkyl ether-based PROTAC linker can be used in the synthesis of PROTACs.
Product information
CAS Number: 10436-21-2
Molecular Weight: 344.45
Formula: C17H32N2O5
Chemical Name: 5-[(6-{[(tert-butoxy)carbonyl]amino}hexyl)carbamoyl]pentanoic acid
Smiles: CC(C)(C)OC(=O)NCCCCCCNC(=O)CCCCC(O)=O
InChiKey: VCIQUSOFCWVBLU-UHFFFAOYSA-N
InChi: InChI=1S/C17H32N2O5/c1-17(2,3)24-16(23)19-13-9-5-4-8-12-18-14(20)10-6-7-11-15(21)22/h4-13H2,1-3H3,(H,18,20)(H,19,23)(H,21,22)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Products are for research use only. Not for human use.
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