Description
A-674563 is a potent, orally available Akt1 inhibitor with an IC50 value of 11nM. Also displays activity against PKA and CDK2 with IC50 values of 16nM and 46nM respectively.
Product information
CAS Number: 552325-73-2
Molecular Weight: 358.44
Formula: C22H22N4O
Chemical Name: (2S)-1-{[5-(3-methyl-2H-indazol-5-yl)pyridin-3-yl]oxy}-3-phenylpropan-2-amine
Smiles: CC1NN=C2C=CC(=CC2=1)C1=CN=CC(=C1)OC[C@@H](N)CC1C=CC=CC=1
InChiKey: BPNUQXPIQBZCMR-IBGZPJMESA-N
InChi: InChI=1S/C22H22N4O/c1-15-21-11-17(7-8-22(21)26-25-15)18-10-20(13-24-12-18)27-14-19(23)9-16-5-3-2-4-6-16/h2-8,10-13,19H,9,14,23H2,1H3,(H,25,26)/t19-/m0/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥360 days if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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