SB-742457


Catalog No. Size PriceQuantity
M10417-2 Solid 2 mg $90
M10417-10 Solid 10 mg $270

Description

Intepirdine, also known as SB-742457 and RVT-101, is a selective 5-HT6 receptor antagonist with potential cognition, memory, and learning-enhancing effects. It was under development by GlaxoSmithKline for the treatment of Alzheimer's disease and demonstrated some preliminary efficacy in phase II clinical trials. SB742457 can reverse age-related declines in delayed non-match-to-sample performance (DNMS). SB742457 shows increasing pro-cognitive effects in patients with AD.

Product information

CAS Number: 607742-69-8

Molecular Weight: 353.44

Formula: C19H19N3O2S

Chemical Name: 3-(benzenesulfonyl)-8-(piperazin-1-yl)quinoline

Smiles: O=S(=O)(C1C=CC=CC=1)C1=CN=C2C(=CC=CC2=C1)N1CCNCC1

InChiKey: JJZFWROHYSMCMU-UHFFFAOYSA-N

InChi: InChI=1S/C19H19N3O2S/c23-25(24,16-6-2-1-3-7-16)17-13-15-5-4-8-18(19(15)21-14-17)22-11-9-20-10-12-22/h1-8,13-14,20H,9-12H2

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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