Apoptosis is a complex series of protease pathways designed to kill cells in a selective manner. Apoptosis can simplistically be defined into linear pathways; however, each pathway is subject to fine control of its activity at multiple points. Other forms of cell survival regulation such as autophagy can impact on the outcome of a primary apoptosis signal. Alternatively, autophagy can be a primary signal that feeds into apoptosis resulting in cell killing. Thus, despite many years of investigation, there still remain many unanswered questions in the regulation of cell survival by apoptosis.
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(-)-Huperzine A
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(20S)-Protopanaxadiol
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(5Z, 2E)-CU-3
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(E)-Flavokawain A
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(R)-(+)-Etomoxir Sodium Salt
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(R)-CR8
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(R)-CR8 trihydrochloride
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(S)-(+)-Rolipram
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17-AAG
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2-Deoxy-D-glucose
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2-Methoxyestradiol
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3-Nitropropanoic acid
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3BDO
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4-Hydroperoxy cyclophosphamide
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4SC-202 free base
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5-Fluorouracil
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6-Thioguanine
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9-cis-Retinoic acid
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