- LAK-cell-originated protein kinase (TOPK), a MAPKK-like kinase, is crucial for neural progenitor cell proliferation. Phylogenetic tree shows that it is a branch between MEK1/2 and MKK7 and is involved in various biological processes such as tumor development, cell cycle, cell proliferation, apoptosis and inflammation.
HI-TOPK-032, TOPK inhibitor
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