Smoothened (SMO), a class Frizzled G protein-coupled receptor (class F GPCR), transduces the Hedgehog signal across the cell membrane. Sterols can bind to its extracellular cysteine-rich domain (CRD) and to several sites in the seven transmembrane helices (7-TMs) of SMO.
20(S)-Hydroxycholesterol
From $230
ALLO-2 - CAS# 1357350-60-7
From $195
BMS-833923 - CAS# 1059734-66-5
From $85
Halcinonide - CAS# 3093-35-4
From $80
HhAntag
From $120
Jervine
From $125
LDE225 Diphosphate
From $80
LY2940680
From $100
PF-04449913
From $105
PF-5274857
From $100
