(4-Acetamidocyclohexyl) nitrate


Catalog No. Size PriceQuantity
M15467-2 Contact sales@xcessbio.com for quotation $100

Description

(4-Acetamidocyclohexyl) nitrate (BM121307) is a guanylate cyclase activator.

Product information

CAS Number: 137213-91-3

Molecular Weight: 202.21

Formula: C8H14N2O4

Chemical Name: (1r,4r)-4-acetamidocyclohexyl nitrate

Smiles: CC(=O)N[C@@H]1CC[C@H](CC1)O[N+]([O-])=O

InChiKey: ZGGZZKIXIOEJCM-ZKCHVHJHSA-N

InChi: InChI=1S/C8H14N2O4/c1-6(11)9-7-2-4-8(5-3-7)14-10(12)13/h7-8H,2-5H2,1H3,(H,9,11)/t7-,8-

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vivo:

The elimination of BM121307 and its metabolites via urine and feces amount to 76.5% after oral application, and to 80.7% of the applied dose after intravenous application. The major amount of radioactivity is eliminated via urine (69.4% and 73.6% of the dose, respectively), whereas the fecal elimination is found to be negligible. Investigations of the urinary samples show that the drug is metabolized to a high percentage trans-N-(4-Hydroxycyclohexyl) acetamide is the main metabolite; 73% of the radioactive compounds (after p.o.-administration and 69% after intravenous application could be identified as the alcohol of BM121307; the amounts of the drug totaled 9% and 13%, respectively.

Products are for research use only. Not for human use.

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