Description
(Rac)-OSMI-1 is the racemate of OSMI-1. OSMI-1 is a cell-permeable O-GlcNAc transferase (OGT) inhibitor with an IC50 value of 2.7 μM. OSMI-1 inhibits protein O-linked N-acetylglucosamine (O-GlcNAcylation) in several mammalian cell lines without qualitatively altering cell surface N- or O-linked glycans.
Product information
Molecular Weight: 563.64
Formula: C28H25N3O6S2
Chemical Name: N-(furan-2-ylmethyl)-2-(2-methoxyphenyl)-2-((2-oxo-1, 2-dihydroquinoline)-6-sulfonamido)-N-(thiophen-2-ylmethyl)acetamide
Smiles: COC1=CC=CC=C1C(NS(=O)(=O)C1=CC2C=CC(=O)NC=2C=C1)C(=O)N(CC1=CC=CO1)CC1=CC=CS1
InChiKey: IYIGLWQQAMROOF-UHFFFAOYSA-N
InChi: InChI=1S/C28H25N3O6S2/c1-36-25-9-3-2-8-23(25)27(28(33)31(17-20-6-4-14-37-20)18-21-7-5-15-38-21)30-39(34,35)22-11-12-24-19(16-22)10-13-26(32)29-24/h2-16,27,30H,17-18H2,1H3,(H,29,32)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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