Zalunfiban dihydrochloride


Catalog No. Size PriceQuantity
M17417-C Contact sales@xcessbio.com for quotation $100

Description

Zalunfiban (RUC-4) dihydrochloride is a potent, selective platelet αIIbβ3 antagonist (IC50=45 nM). Zalunfiban dihydrochloride can be used for the research of myocardial infarction (MI).

Product information

Molecular Weight: 459.35

Formula: C16H20Cl2N8O2S

Chemical Name: 2-amino-N-(5-(5-oxo-7-(piperazin-1-yl)-5H-[1, 3, 4]thiadiazolo[3, 2-a]pyrimidin-2-yl)pyridin-3-yl)acetamide dihydrochloride

Smiles: Cl.Cl.NCC(=O)NC1=CC(=CN=C1)C1=NN2C(=NC(=CC2=O)N2CCNCC2)S1

InChiKey: GVDRCFLSNUIMCT-UHFFFAOYSA-N

InChi: InChI=1S/C16H18N8O2S.2ClH/c17-7-13(25)20-11-5-10(8-19-9-11)15-22-24-14(26)6-12(21-16(24)27-15)23-3-1-18-2-4-23;;/h5-6,8-9,18H,1-4,7,17H2,(H,20,25);2*1H

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vivo:

Zalunfiban dihydrochloride (1~3.86 mg/kg; s.c.; 24 hours) makes platelet aggregation performed. Zalunfiban dihydrochloride (1~3.86 mg/kg; i.m.; 4.5 hours) leads to the onset of high-grade inhibition of platelet aggregation within 15–30 minutes that lasts from ~2 to >4.5 hours in a dose dependent manner.

Products are for research use only. Not for human use.

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