Description
ZD-9379 is a potent, orally active, and brain penetrant full antagonist at the glycine site of the NMDA receptor. ZD-9379 has neuroprotective effect.
Product information
CAS Number: 170142-20-8
Molecular Weight: 383.79
Formula: C19H14ClN3O4
Chemical Name: 7-chloro-4-hydroxy-2-(4-methoxy-2-methylphenyl)-1H,2H,5H,10H-pyridazino[4,5-b]quinoline-1,10-dione
Smiles: CC1=CC(=CC=C1N1N=C(O)C2NC3C=C(Cl)C=CC=3C(=O)C=2C1=O)OC
InChiKey: PSTDMIAVUUYOOQ-UHFFFAOYSA-N
InChi: InChI=1S/C19H14ClN3O4/c1-9-7-11(27-2)4-6-14(9)23-19(26)15-16(18(25)22-23)21-13-8-10(20)3-5-12(13)17(15)24/h3-8H,1-2H3,(H,21,24)(H,22,25)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vivo:
ZD-9379 (5 mg/kg) reduces number of spreading depressions and infarct size in rats with permanent middle cerebral artery occlusion.
Products are for research use only. Not for human use.
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