(Rac)-HAMI 3379


Catalog No. Size PriceQuantity
M21954-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

(Rac)-HAMI 3379 is the racemate of HAMI 3379. HAMI 3379 is a potent and selective Cysteinyl leukotriene (CysLT2) receptor antagonist.

Product information

CAS Number: 712313-35-4

Molecular Weight: 595.72

Formula: C34H45NO8

Chemical Name: 3-[(3-carboxycyclohexyl)carbamoyl]-4-(3-{4-[4-(cyclohexyloxy)butoxy]phenyl}propoxy)benzoic acid

Smiles: OC(=O)C1CC(CCC1)NC(=O)C1=CC(=CC=C1OCCCC1C=CC(=CC=1)OCCCCOC1CCCCC1)C(O)=O

InChiKey: HRJWSEPIRZRGCL-UHFFFAOYSA-N

InChi: InChI=1S/C34H45NO8/c36-32(35-27-10-6-9-25(22-27)33(37)38)30-23-26(34(39)40)15-18-31(30)43-21-7-8-24-13-16-29(17-14-24)42-20-5-4-19-41-28-11-2-1-3-12-28/h13-18,23,25,27-28H,1-12,19-22H2,(H,35,36)(H,37,38)(H,39,40)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 100 mg/mL (167.86 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

In a CysLT2 receptor reporter cell line, HAMI3379 antagonizes leukotriene D4- (LTD4-) and leukotriene C4- (LTC4-) induced intracellular calcium mobilization with IC50 values of 3.8 nM and 4.4 nM respectively.

Products are for research use only. Not for human use.

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