Description
ZINC03129319 is a dengue virus (DENV) NS2B-NS3 protease inhibitor extracted from patent US20150141521A1, has inhibition constants (Ki1) of 92 μM and Ki3 of 20 μM.
Product information
CAS Number: 1777807-64-3
Molecular Weight: 490.51
Formula: C24H14N2O6S2
Chemical Name: (1'S,7'S)-1,1'',3,3''-tetrahydrodispiro[indene-2,4'-[5,11]dithia-[3,9]diazatricyclo[7.3.0.0³,⁷]dodecane-10',2''-indene]-1,1'',2',3,3'',8'-hexone
Smiles: O=C1[C@H]2CSC3(C(=O)C4=CC=CC=C4C3=O)N2C(=O)[C@H]2CSC3(C(=O)C4=CC=CC=C4C3=O)N12
InChiKey: GBYAWPJNMFAKDJ-HZPDHXFCSA-N
InChi: InChI=1S/C24H14N2O6S2/c27-17-11-5-1-2-6-12(11)18(28)23(17)25-15(9-33-23)22(32)26-16(21(25)31)10-34-24(26)19(29)13-7-3-4-8-14(13)20(24)30/h1-8,15-16H,9-10H2/t15-,16-/m1/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO : 41.67 mg/mL (84.95 mM; Need ultrasonic).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
ZINC03129319 inhibits DENV NS2B-NS3 protease with Ki1 of 92±15 μM and Ki3 of 20±4 μM.
Products are for research use only. Not for human use.
Payment & Security
Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.