(R)-Nicardipine


Catalog No. Size PriceQuantity
M27449-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

(R)-Nicardipine ((R)-YC-93 free base) is the less active R enantiomer of Nicardipine. Nicardipine (YC-93) is a calcium channel blocker with an IC50 of 1 μM for blocking cardiac calcium channels. Nicardipine acts as an agent for chronic stable angina and for controlling blood pressure.

Product information

CAS Number: 76093-35-1

Molecular Weight: 479.52

Formula: C26H29N3O6

Chemical Name: 3-{2-[benzyl(methyl)amino]ethyl} 5-methyl (4R)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

Smiles: COC(=O)C1[C@H](C(C(=O)OCCN(C)CC2C=CC=CC=2)=C(C)NC=1C)C1=CC(=CC=C1)[N+]([O-])=O

InChiKey: ZBBHBTPTTSWHBA-XMMPIXPASA-N

InChi: InChI=1S/C26H29N3O6/c1-17-22(25(30)34-4)24(20-11-8-12-21(15-20)29(32)33)23(18(2)27-17)26(31)35-14-13-28(3)16-19-9-6-5-7-10-19/h5-12,15,24,27H,13-14,16H2,1-4H3/t24-/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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